4OYX
 
 | | Human solAC Complexed with AMPCPP | | 分子名称: | Adenylate cyclase type 10, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Vinkovic, M. | | 登録日 | 2014-02-13 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
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4OYP
 | | Human solAC Complexed with 1-Benzofuran-2-carboxylic acid | | 分子名称: | 1-benzofuran-2-carboxylic acid, Adenylate cyclase type 10, CHLORIDE ION | | 著者 | Vinkovic, M. | | 登録日 | 2014-02-12 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
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4OZ2
 | | Human solAC Complexed with 4-(4-Fluorophenyl)-3-methyl-1H-pyrazole | | 分子名称: | 4-(4-fluorophenyl)-3-methyl-1H-pyrazole, Adenylate cyclase type 10, CHLORIDE ION, ... | | 著者 | Vinkovic, M. | | 登録日 | 2014-02-13 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9, 2014
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6LDD
 | | Structure of Bifidobacterium dentium beta-glucuronidase complexed with C6-propyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)-2-propyl-piperidine-3-carboxylic acid, LacZ1 Beta-galactosidase | | 著者 | Lin, H.-Y, Hsieh, T.-J, Lin, C.-H. | | 登録日 | 2019-11-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LEJ
 | | Structure of E. coli beta-glucuronidase complex with C6-propyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)-2-propyl-piperidine-3-carboxylic acid, Beta-D-glucuronidase | | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | | 登録日 | 2019-11-25 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.617 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LEL
 | | Structure of E. coli beta-glucuronidase complex with C6-hexyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-2-hexyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid, Beta-D-glucuronidase | | 著者 | Lin, H.-Y, Kuo, Y.-H, Lin, C.-H. | | 登録日 | 2019-11-25 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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6LDC
 | | Structure of Bifidobacterium dentium beta-glucuronidase complexed with C6-nonyl uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-2-nonyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid, LacZ1 Beta-galactosidase | | 著者 | Lin, H.-Y, Hsieh, T.-J, Lin, C.-H. | | 登録日 | 2019-11-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.181 Å) | | 主引用文献 | Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Commun Biol, 4, 2021
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3T26
 | | Orthorhombic trypsin (bovine) in the presence of sarcosine | | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3T29
 | | TMAO-grown trigonal trypsin (bovine) | | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3T2J
 | | Tetragonal thermolysin in the presence of betaine | | 分子名称: | CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Cahn, J, Hti Lar Seng, N.S, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3TDD
 | | Crystal structure of yeast CP in complex with Belactosin C | | 分子名称: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | | 著者 | Korotkov, V.S, Ludwig, A, Larionov, O.V, Lygin, A.V, Groll, M, de Meijere, A. | | 登録日 | 2011-08-10 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Synthesis and biological activity of optimized belactosin C congeners.
Org.Biomol.Chem., 9, 2011
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3RF4
 | | Ancylostoma ceylanicum mif in complex with furosemide | | 分子名称: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, ACETATE ION, IMIDAZOLE, ... | | 著者 | Cho, Y, Lolis, E. | | 登録日 | 2011-04-05 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
Chem.Biol., 18, 2011
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3T2H
 | | Tetragonal thermolysin in the presence of TMAO | | 分子名称: | CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Cahn, J, Hti Lar Seng, N.S, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3T28
 | | TMAO-grown trypsin (bovine)-previously unreported tetragonal crystal form | | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | | 著者 | Cahn, J, Venkat, M, Saxby, S, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3T2I
 | | Tetragonal thermolysin in the presence of sarcosine | | 分子名称: | CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Cahn, J, Hti Lar Seng, N.S, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3T2A
 | | TMAO-grown cubic insulin (porcine) | | 分子名称: | Insulin A chain, Insulin B chain, trimethylamine oxide | | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2012-01-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3RF5
 | | Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide | | 分子名称: | 2-[(furan-2-ylmethyl)amino]benzoic acid, ACETATE ION, IMIDAZOLE, ... | | 著者 | Cho, Y, Lolis, E. | | 登録日 | 2011-04-05 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
Chem.Biol., 18, 2011
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3T25
 | | TMAO-grown orthorhombic trypsin (bovine) | | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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5VQ5
 | | Crystal Structure of the Lectin Domain From the F17-like Adhesin, UclD | | 分子名称: | Adhesin, IODIDE ION | | 著者 | Klein, R.D, Spaulding, C.N, Dodson, K.W, Pinkner, J.S, Hultgren, S.J, Fremont, D. | | 登録日 | 2017-05-08 | | 公開日 | 2017-05-24 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.
Nature, 546, 2017
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1IHI
 | | Crystal Structure of Human Type III 3-alpha-Hydroxysteroid Dehydrogenase/Bile Acid Binding Protein (AKR1C2) Complexed with NADP+ and Ursodeoxycholate | | 分子名称: | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, ISO-URSODEOXYCHOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Jin, Y, Stayrook, S.E, Albert, R.H, Palackal, N.T, Penning, T.M, Lewis, M. | | 登録日 | 2001-04-19 | | 公開日 | 2001-10-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.
Biochemistry, 40, 2001
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3T27
 | | Orthorhombic trypsin (bovine) in the presence of betaine | | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | | 著者 | Venkat, M, Saxby, C, Cahn, J, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
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3UW4
 | | Crystal structure of cIAP1 BIR3 bound to GDC0152 | | 分子名称: | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 4, GDC0152, ... | | 著者 | Maurer, B, Hymowitz, S. | | 登録日 | 2011-11-30 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152).
J.Med.Chem., 55, 2012
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3UW5
 | | Crystal structure of the BIR domain of MLIAP bound to GDC0152 | | 分子名称: | Baculoviral IAP repeat-containing protein 7, Baculoviral IAP repeat-containing protein 4, GDC-0152, ... | | 著者 | Maurer, B, Hymowitz, S.G. | | 登録日 | 2011-11-30 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152).
J.Med.Chem., 55, 2012
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3VB7
 | | Crystal structure of SARS-CoV 3C-like protease with M4Z | | 分子名称: | 1,2-ETHANEDIOL, 3C-like proteinase, GLYCEROL, ... | | 著者 | Chuck, C.P, Wong, K.B. | | 登録日 | 2011-12-31 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases
Eur.J.Med.Chem., 59C, 2012
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3VB6
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