3RF4
Ancylostoma ceylanicum mif in complex with furosemide
Summary for 3RF4
Entry DOI | 10.2210/pdb3rf4/pdb |
Related | 2OS5 3RF5 |
Descriptor | Macrophage migration inhibitory factor, 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, IMIDAZOLE, ... (6 entities in total) |
Functional Keywords | protein-small molecule complex, isomerase, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
Biological source | Ancylostoma ceylanicum |
Total number of polymer chains | 3 |
Total formula weight | 40476.38 |
Authors | |
Primary citation | Cho, Y.,Vermeire, J.J.,Merkel, J.S.,Leng, L.,Du, X.,Bucala, R.,Cappello, M.,Lolis, E. Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem.Biol., 18:1089-1101, 2011 Cited by PubMed: 21944748DOI: 10.1016/j.chembiol.2011.07.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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