3RF4

Ancylostoma ceylanicum mif in complex with furosemide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005125	molecular_function	cytokine activity
A	0005126	molecular_function	cytokine receptor binding
A	0005615	cellular_component	extracellular space
A	0007165	biological_process	signal transduction
A	0046872	molecular_function	metal ion binding
A	0050178	molecular_function	phenylpyruvate tautomerase activity
B	0005125	molecular_function	cytokine activity
B	0005126	molecular_function	cytokine receptor binding
B	0005615	cellular_component	extracellular space
B	0007165	biological_process	signal transduction
B	0046872	molecular_function	metal ion binding
B	0050178	molecular_function	phenylpyruvate tautomerase activity
C	0005125	molecular_function	cytokine activity
C	0005126	molecular_function	cytokine receptor binding
C	0005615	cellular_component	extracellular space
C	0007165	biological_process	signal transduction
C	0046872	molecular_function	metal ion binding
C	0050178	molecular_function	phenylpyruvate tautomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE FUN A 201

Chain	Residue
A	PRO1
A	HOH259
A	HOH456
C	HIS49
C	ILE95
A	MET2
A	LYS32
A	ARG36
A	SER63
A	ILE64
A	VAL106
A	PHE108
A	VAL113

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IMD A 117

Chain	Residue
A	GLY44
A	ARG46
B	ASP11
B	ZN119
B	ACT122

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 118

Chain	Residue
A	ASP11
A	ACT120
A	HOH243
C	IMD118

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 119

Chain	Residue
A	GLU20
A	GLU20
A	ASP24
A	ASP24

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 120

Chain	Residue
A	ASP11
A	ZN118
A	HOH365
C	ARG46
C	IMD118

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT A 121

Chain	Residue
A	ASP92

---

site_id	AC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE FUN B 202

Chain	Residue
A	HIS49
A	ILE95
B	PRO1
B	MET2
B	LYS32
B	ARG36
B	ILE64
B	VAL106
B	PHE108
B	VAL113
B	HOH458
B	HOH459

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IMD B 117

Chain	Residue
A	ASP70
B	GLY44
B	ARG46
B	ACT121
C	ASP11
C	ZN119

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IMD B 118

Chain	Residue
B	ASP71
B	HOH155
B	HOH292

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 119

Chain	Residue
A	IMD117
B	ASP11
B	ACT122
B	HOH242

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 120

Chain	Residue
B	GLU20
B	ASP24
C	GLU20
C	ASP24

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT B 121

Chain	Residue
A	ASP70
B	ARG46
B	ARG53
B	IMD117
C	ASP11
C	ZN119

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT B 122

Chain	Residue
A	ARG46
A	ARG53
A	IMD117
B	ASP11
B	ZN119

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT B 123

Chain	Residue
B	ASP92

---

site_id	BC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE FUN C 203

Chain	Residue
B	HIS49
B	ILE95
C	PRO1
C	MET2
C	LYS32
C	ARG36
C	ILE64
C	VAL106
C	PHE108
C	VAL113
C	HOH460
C	HOH463

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IMD C 117

Chain	Residue
C	ALA116
C	ALA116

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IMD C 118

Chain	Residue
A	ASP11
A	ZN118
A	ACT120
C	GLY44
C	ARG46

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 119

Chain	Residue
A	ASP70
B	IMD117
B	ACT121
C	ASP11

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 120

Chain	Residue
C	ACT121
C	ASP71
C	ASP71
C	ACT121

---

site_id	CC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACT C 121

Chain	Residue
C	MET30
C	ASN31
C	ALA66
C	SER68
C	ASP71
C	ASP71
C	ZN120
C	ZN120
C	HOH245

---

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT C 122

Chain	Residue
C	ASP92

---