3TDD
Crystal structure of yeast CP in complex with Belactosin C
Summary for 3TDD
Entry DOI | 10.2210/pdb3tdd/pdb |
Related | 1RYP 3E47 |
Descriptor | Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total) |
Functional Keywords | ubiquitin, inhibitor, proteasome, drug development, primed substrate binding channel, beta-sandwich flanked by alpha-helices, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
Total number of polymer chains | 28 |
Total formula weight | 705473.70 |
Authors | Korotkov, V.S.,Ludwig, A.,Larionov, O.V.,Lygin, A.V.,Groll, M.,de Meijere, A. (deposition date: 2011-08-10, release date: 2011-10-12, Last modification date: 2023-09-13) |
Primary citation | Korotkov, V.S.,Ludwig, A.,Larionov, O.V.,Lygin, A.V.,Groll, M.,de Meijere, A. Synthesis and biological activity of optimized belactosin C congeners. Org.Biomol.Chem., 9:7791-7798, 2011 Cited by PubMed: 21946808DOI: 10.1039/c1ob05661a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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