3TDD

Crystal structure of yeast CP in complex with Belactosin C

Summary for 3TDD

• Entry DOI: 10.2210/pdb3tdd/pdb
• Related: 1RYP 3E47
• Descriptor: Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total)
• Functional Keywords: ubiquitin, inhibitor, proteasome, drug development, primed substrate binding channel, beta-sandwich flanked by alpha-helices, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Cellular location: Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
• Total number of polymer chains: 28
• Total formula weight: 705473.70

Authors

Korotkov, V.S.,Ludwig, A.,Larionov, O.V.,Lygin, A.V.,Groll, M.,de Meijere, A. (deposition date: 2011-08-10, release date: 2011-10-12, Last modification date: 2023-09-13)

• Primary citation: Korotkov, V.S.,Ludwig, A.,Larionov, O.V.,Lygin, A.V.,Groll, M.,de Meijere, A.; Synthesis and biological activity of optimized belactosin C congeners.; Org.Biomol.Chem., 9:7791-7798, 2011; PubMed: 21946808; DOI: 10.1039/c1ob05661a

Experimental method

X-RAY DIFFRACTION (2.7 Å)