4OZ2
Human solAC Complexed with 4-(4-Fluorophenyl)-3-methyl-1H-pyrazole
Summary for 4OZ2
Entry DOI | 10.2210/pdb4oz2/pdb |
Related | 4OYA 4OYB 4OYI 4OYM 4OYO 4OYP 4OYW 4OYX 4OYZ 4OZ3 |
Descriptor | Adenylate cyclase type 10, 4-(4-fluorophenyl)-3-methyl-1H-pyrazole, GLYCEROL, ... (5 entities in total) |
Functional Keywords | protein-ligand complex, lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q96PN6 |
Total number of polymer chains | 1 |
Total formula weight | 53954.76 |
Authors | Vinkovic, M. (deposition date: 2014-02-13, release date: 2014-04-02, Last modification date: 2023-12-27) |
Primary citation | Saalau-Bethell, S.M.,Berdini, V.,Cleasby, A.,Congreve, M.,Coyle, J.E.,Lock, V.,Murray, C.W.,O'Brien, M.A.,Rich, S.J.,Sambrook, T.,Vinkovic, M.,Yon, J.R.,Jhoti, H. Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9:823-832, 2014 Cited by PubMed: 24616449DOI: 10.1002/cmdc.201300480 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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