4OYX

Human solAC Complexed with AMPCPP

Summary for 4OYX

Entry DOI	10.2210/pdb4oyx/pdb
Related	4OYA 4OYB 4OYI 4OYM 4OYO 4OYP 4OYW 4OYZ 4OZ2 4OZ3
Descriptor	Adenylate cyclase type 10, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, CALCIUM ION, ... (5 entities in total)
Functional Keywords	protein-substrate analogue complex, lyase
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q96PN6
Total number of polymer chains	1
Total formula weight	54047.57
Authors	Vinkovic, M. (deposition date: 2014-02-13, release date: 2014-04-02, Last modification date: 2023-12-27)
Primary citation	Saalau-Bethell, S.M.,Berdini, V.,Cleasby, A.,Congreve, M.,Coyle, J.E.,Lock, V.,Murray, C.W.,O'Brien, M.A.,Rich, S.J.,Sambrook, T.,Vinkovic, M.,Yon, J.R.,Jhoti, H. Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9:823-832, 2014 Cited by PubMed: 24616449 DOI: 10.1002/cmdc.201300480 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation