4OYM
Human solAC Complexed with (4-Amino-furazan-3-yl)-(3-methoxy-phenyl)-methanone
Summary for 4OYM
Entry DOI | 10.2210/pdb4oym/pdb |
Related | 4OYA 4OYB 4OYI 4OYO 4OYP 4OYW 4OYX 4OYZ 4OZ2 4OZ3 |
Descriptor | Adenylate cyclase type 10, (4-azanyl-1,2,5-oxadiazol-3-yl)-(3-methoxyphenyl)methanone, GLYCEROL, ... (4 entities in total) |
Functional Keywords | lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q96PN6 |
Total number of polymer chains | 1 |
Total formula weight | 53870.22 |
Authors | Vinkovic, M. (deposition date: 2014-02-12, release date: 2014-04-02, Last modification date: 2023-12-27) |
Primary citation | Saalau-Bethell, S.M.,Berdini, V.,Cleasby, A.,Congreve, M.,Coyle, J.E.,Lock, V.,Murray, C.W.,O'Brien, M.A.,Rich, S.J.,Sambrook, T.,Vinkovic, M.,Yon, J.R.,Jhoti, H. Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9:823-832, 2014 Cited by PubMed: 24616449DOI: 10.1002/cmdc.201300480 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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