4OZ2

Human solAC Complexed with 4-(4-Fluorophenyl)-3-methyl-1H-pyrazole

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009190	biological_process	cyclic nucleotide biosynthetic process
A	0035556	biological_process	intracellular signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue 1Z6 A 501

Chain	Residue
A	ALA97
A	HOH1045
A	GLY98
A	PHE336
A	PHE338
A	LEU345
A	VAL406
A	VAL411
A	ASN412
A	ALA415

---

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 502

Chain	Residue
A	LYS95
A	PHE96
A	ALA97
A	ALA100
A	LEU101
A	LEU102
A	PHE336
A	HOH1016

---

site_id	AC3
Number of Residues	9
Details	binding site for residue GOL A 503

Chain	Residue
A	ILE24
A	VAL25
A	GLY27
A	HIS28
A	PHE29
A	LEU261
A	SER264
A	TYR268
A	HOH923

---

site_id	AC4
Number of Residues	9
Details	binding site for residue GOL A 504

Chain	Residue
A	THR322
A	LEU325
A	LYS326
A	GLY330
A	GLN331
A	ILE332
A	HOH857
A	HOH1023
A	HOH1074

---

site_id	AC5
Number of Residues	3
Details	binding site for residue CL A 505

Chain	Residue
A	LYS95
A	VAL167
A	HOH1020

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00099

Chain	Residue	Details
A	ASP47
A	ILE48
A	ASP99

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:24567411, ECO:0000269|PubMed:24616449, ECO:0007744|PDB:4CLL, ECO:0007744|PDB:4OYZ

Chain	Residue	Details
A	LYS95
A	VAL167
A	ARG176
A	MET337

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:25040695, ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0007744|PDB:4USW

Chain	Residue	Details
A	LYS144
A	VAL406

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0000305|PubMed:25040695

Chain	Residue	Details
A	ASN412

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