3RF5
Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide
Summary for 3RF5
Entry DOI | 10.2210/pdb3rf5/pdb |
Related | 2OS5 3RF4 |
Descriptor | Macrophage migration inhibitory factor, 2-[(furan-2-ylmethyl)amino]benzoic acid, IMIDAZOLE, ... (6 entities in total) |
Functional Keywords | protein-small molecule complex, isomerase, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
Biological source | Ancylostoma ceylanicum |
Total number of polymer chains | 3 |
Total formula weight | 39885.92 |
Authors | |
Primary citation | Cho, Y.,Vermeire, J.J.,Merkel, J.S.,Leng, L.,Du, X.,Bucala, R.,Cappello, M.,Lolis, E. Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem.Biol., 18:1089-1101, 2011 Cited by PubMed: 21944748DOI: 10.1016/j.chembiol.2011.07.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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