3RF5
Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005125 | molecular_function | cytokine activity |
| A | 0005126 | molecular_function | cytokine receptor binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0007165 | biological_process | signal transduction |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050178 | molecular_function | phenylpyruvate tautomerase activity |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0005126 | molecular_function | cytokine receptor binding |
| B | 0005615 | cellular_component | extracellular space |
| B | 0007165 | biological_process | signal transduction |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050178 | molecular_function | phenylpyruvate tautomerase activity |
| C | 0005125 | molecular_function | cytokine activity |
| C | 0005126 | molecular_function | cytokine receptor binding |
| C | 0005615 | cellular_component | extracellular space |
| C | 0007165 | biological_process | signal transduction |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050178 | molecular_function | phenylpyruvate tautomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE FUZ A 202 |
| Chain | Residue |
| A | PRO1 |
| C | HIS49 |
| C | ILE95 |
| A | MET2 |
| A | LYS32 |
| A | ARG36 |
| A | SER63 |
| A | ILE64 |
| A | VAL106 |
| A | PHE108 |
| A | VAL113 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IMD A 117 |
| Chain | Residue |
| A | ASP70 |
| A | ZN119 |
| A | ACT124 |
| B | GLY44 |
| B | ARG46 |
| C | ASP11 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD A 118 |
| Chain | Residue |
| A | GLY44 |
| A | ARG46 |
| A | ACT123 |
| B | ASP11 |
| B | ZN117 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 119 |
| Chain | Residue |
| A | ASP70 |
| A | IMD117 |
| A | ACT124 |
| C | ASP11 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 120 |
| Chain | Residue |
| A | ASP11 |
| A | ACT122 |
| A | HOH140 |
| C | IMD117 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 121 |
| Chain | Residue |
| A | GLU20 |
| A | GLU20 |
| A | ASP24 |
| A | ASP24 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 122 |
| Chain | Residue |
| A | ASP11 |
| A | ZN120 |
| C | ARG46 |
| C | IMD117 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 123 |
| Chain | Residue |
| A | ARG46 |
| A | IMD118 |
| B | ASP11 |
| B | ZN117 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 124 |
| Chain | Residue |
| A | ASP70 |
| A | IMD117 |
| A | ZN119 |
| B | ARG46 |
| B | ARG53 |
| C | ASP11 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FUZ B 201 |
| Chain | Residue |
| A | HIS49 |
| A | ILE95 |
| B | PRO1 |
| B | MET2 |
| B | LYS32 |
| B | ARG36 |
| B | ILE64 |
| B | VAL106 |
| B | PHE108 |
| B | VAL113 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 117 |
| Chain | Residue |
| A | IMD118 |
| A | ACT123 |
| A | HOH181 |
| B | ASP11 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 118 |
| Chain | Residue |
| B | GLU20 |
| B | ASP24 |
| C | GLU20 |
| C | ASP24 |
| site_id | BC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FUZ C 203 |
| Chain | Residue |
| B | HIS49 |
| B | ILE95 |
| C | PRO1 |
| C | MET2 |
| C | LYS32 |
| C | ARG36 |
| C | ILE64 |
| C | VAL106 |
| C | PHE108 |
| C | VAL113 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD C 117 |
| Chain | Residue |
| A | ASP11 |
| A | ZN120 |
| A | ACT122 |
| C | GLY44 |
| C | ARG46 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 118 |
| Chain | Residue |
| C | ASP71 |
| C | ASP71 |
| C | ACT120 |
| C | ACT120 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN C 119 |
| Chain | Residue |
| C | ALA116 |
| C | ALA116 |
| site_id | BC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ACT C 120 |
| Chain | Residue |
| C | MET30 |
| C | ASN31 |
| C | ALA66 |
| C | ALA66 |
| C | SER68 |
| C | ASP71 |
| C | ASP71 |
| C | ARG74 |
| C | ZN118 |
| C | ZN118 |
| C | HOH181 |
| C | HOH194 |
