PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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4RAU	crystal structure of RTOFab in complex with human PF4 分子名称: Platelet factor 4, RTOFab heavy chain, RTOFab light chain 著者 Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. 登録日 2014-09-11 公開日 2016-03-16 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 crystal structure of RTOFab in complex with platelet factor 4 To be Published
8SJD	Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon. 分子名称: DNA (46-MER), DNA (55-MER), DNA (8-MER), ... 著者 Lannes, L, Dyda, F. 登録日 2023-04-17 公開日 2023-08-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding. Nat Commun, 14, 2023
1CF7	STRUCTURAL BASIS OF DNA RECOGNITION BY THE HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTOR E2F-DP 分子名称: DNA (5'-D(*AP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*GP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*CP*CP*GP*CP*GP*CP*GP*AP*AP*AP*A)-3'), PROTEIN (TRANSCRIPTION FACTOR DP-2), ... 著者 Zheng, N, Fraenkel, E, Pabo, C.O, Pavletich, N.P. 登録日 1999-03-24 公開日 1999-04-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev., 13, 1999
3PSI	Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(239-1451) 分子名称: Transcription elongation factor SPT6 著者 Close, D, Hill, C.P, Johnson, S.J. 登録日 2010-12-01 公開日 2011-03-30 最終更新日 2011-08-03 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
3PSF	Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(236-1259) 分子名称: Transcription elongation factor SPT6 著者 Close, D, Hill, C.P. 登録日 2010-12-01 公開日 2011-03-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
5FR1	Double acetylated RhoGDI-alpha in complex with RhoA-GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RHO GDP-DISSOCIATION INHIBITOR 1, ... 著者 Kuhlmann, N, Wroblowski, S, Lammers, M. 登録日 2015-12-15 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa. Biochemistry, 55, 2016
7EFA	Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA 分子名称: Adenine DNA glycosylase, Proliferating cell nuclear antigen 著者 Nakamura, T, Nakabeppu, Y, Yamagata, Y. 登録日 2021-03-21 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
5SXM	WDR5 in complex with MLL Win motif peptidomimetic 分子名称: ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5 著者 Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S. 登録日 2016-08-09 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes. J.Biol.Chem., 291, 2016
3PSJ	Crystal Structure of the Spt6 Tandem SH2 Domain from Saccharomyces cerevisiae, Form Se-Spt6 (1247-1451) 分子名称: SULFATE ION, Transcription elongation factor SPT6 著者 Close, D, Hill, C.P. 登録日 2010-12-01 公開日 2011-03-30 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
6FCM	Crystal structure of human PCNA 分子名称: Proliferating cell nuclear antigen 著者 Housset, D, Frachet, P. 登録日 2017-12-20 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
6WGE	Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1 分子名称: DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ... 著者 Shi, Z.B, Gao, H, Bai, X.C, Yu, H. 登録日 2020-04-05 公開日 2020-05-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
6FCN	Crystal structure of human PCNA soaked with p47phox(106-127) peptide 分子名称: Proliferating cell nuclear antigen 著者 Housset, D, Frachet, P. 登録日 2017-12-20 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
7RPW	Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... 著者 Sverzhinsky, A, Pascal, J.M. 登録日 2021-08-04 公開日 2021-11-17 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.38 Å) 主引用文献 Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPO	Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... 著者 Sverzhinsky, A, Pascal, J.M. 登録日 2021-08-03 公開日 2021-11-17 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (4.16 Å) 主引用文献 Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPX	Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA 分子名称: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ... 著者 Sverzhinsky, A, Pascal, J.M. 登録日 2021-08-04 公開日 2021-11-17 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
5XY9	Structure of the MST4 and 14-3-3 complex 分子名称: 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... 著者 Shi, Z.B, Zhou, Z.C. 登録日 2017-07-06 公開日 2018-07-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Structure of the MST4 and 14-3-3 complex To Be Published
5UTZ	Human IL-2/Fab complex 分子名称: Fab 5111 heavy chain, Fab 5111 light chain, GLYCEROL, ... 著者 Jude, K.M, Garcia, K.C. 登録日 2017-02-15 公開日 2018-07-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.747 Å) 主引用文献 A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nat. Med., 24, 2018
8RTY	Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (6.25 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
7DR4	Complex of anti-human IL-2 antibody and human IL-2 分子名称: Interleukin-2, anti-human IL-2 antibody, mouse Ig G, ... 著者 Kim, M.S, Kim, J.E. 登録日 2020-12-25 公開日 2021-04-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity. Oncoimmunology, 10, 2021
6MEV	Structure of JMJD6 bound to Mono-Methyl Arginine. 分子名称: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ... 著者 Lee, S, Zhang, G. 登録日 2018-09-07 公開日 2019-09-18 最終更新日 2020-04-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife, 9, 2020
7Q3O	Structure of CDX1 bound to hydroxymethylated DNA 分子名称: Homeobox protein CDX-1, hydroxymethylated DNA (18-MER) 著者 Morgunova, E, Yin, Y, Popov, A, Taipale, J. 登録日 2021-10-28 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Structure of CDX1 bound to hydroxymethylated DNA To Be Published
3QEX	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite dT 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
8UQE	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density) 分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2023-10-23 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.562 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8UQA	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ... 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2023-10-23 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8UQB	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1) 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2023-10-23 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.484 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024

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