PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4GNC	human SMP30/GNL-1,5-AG complex 分子名称: 1,5-anhydro-D-glucitol, CALCIUM ION, Regucalcin 著者 Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T. 登録日 2012-08-17 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase Plos One, 8, 2013
4EP2	Crystal Structure of inactive single chain wild-type HIV-1 Protease in Complex with the substrate RT-RH 分子名称: GLYCEROL, PHOSPHATE ION, protease, ... 著者 Schiffer, C.A, Mittal, S. 登録日 2012-04-16 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural, kinetic, and thermodynamic studies of specificity designed HIV-1 protease. Protein Sci., 21, 2012
6DE7	Crystal Structure at 4.3 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Interdomain Stabilization 113C-429GCG in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 heavy chain, ... 著者 Gorman, J, Kwong, P.D. 登録日 2018-05-11 公開日 2018-06-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (4.123 Å) 主引用文献 Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer. Cell Host Microbe, 23, 2018
3GO4	Crystal structure of a duf574 family protein (sav_2177) from streptomyces avermitilis ma-4680 at 1.80 A resolution 分子名称: 1,2-ETHANEDIOL, Protein of unknown function DUF574, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-03-18 公開日 2009-04-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Rossmann-fold protein of unknown function (DUF574) (NP_823353.1) from Streptomyces avermitilis MA-4680 at 1.80 A resolution To be published
1WJB	SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, 40 STRUCTURES 分子名称: HIV-1 INTEGRASE, ZINC ION 著者 Clore, G.M, Cai, M, Caffrey, M, Gronenborn, A.M. 登録日 1997-05-13 公開日 1998-05-13 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat.Struct.Biol., 4, 1997
1WJF	SOLUTION STRUCTURE OF H12C MUTANT OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE COMPLEXED TO CADMIUM, NMR, 40 STRUCTURES 分子名称: CADMIUM ION, HIV-1 INTEGRASE 著者 Cai, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-06-11 公開日 1998-12-16 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium. Protein Sci., 7, 1998
2GSS	HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, ... 著者 Oakley, A.J, Rossjohn, J, Parker, M.W. 登録日 1996-10-29 公開日 1997-11-12 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate. Biochemistry, 36, 1997
3NXP	Crystal structure of human prethrombin-1 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Chen, Z, Bush-Pelc, L.A, Di Cera, E. 登録日 2010-07-14 公開日 2010-11-10 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of prethrombin-1. Proc.Natl.Acad.Sci.USA, 107, 2010
3WXC	Crystal Structure of IMP-1 metallo-beta-lactamase complexed with a 3-aminophtalic acid inhibitor 分子名称: 3-(4-hydroxypiperidin-1-yl)benzene-1,2-dicarboxylic acid, Beta-lactamase, ZINC ION 著者 Saito, J, Watanabe, T, Yamada, M. 登録日 2014-07-29 公開日 2014-10-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray crystallographic analysis of IMP-1 metallo-beta-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors Bioorg.Med.Chem.Lett., 24, 2014
1B2I	KRINGLE 2 DOMAIN OF HUMAN PLASMINOGEN: NMR SOLUTION STRUCTURE OF TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID (AMCHA) COMPLEX 分子名称: PROTEIN (PLASMINOGEN), TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID 著者 Marti, D.N, Schaller, J, Llinas, M. 登録日 1999-09-24 公開日 1999-11-19 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of the plasminogen kringle 2-AMCHA complex: 3(1)-helix in homologous domains. Biochemistry, 38, 1999
3O3A	Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2010-07-23 公開日 2010-12-08 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition. J.Med.Chem., 53, 2010
3DEI	Crystal Structures of Caspase-3 with Bound Isoquinoline-1,3,4-trione Derivative Inhibitors 分子名称: (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate, Caspase-3 著者 Wu, J, Du, J, Li, J, Ding, J. 登録日 2008-06-10 公開日 2008-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species J.Biol.Chem., 283, 2008
3DPH	HIV-1 capsid C-terminal domain mutant (L211S) 分子名称: HIV-1 CAPSID PROTEIN 著者 Igonet, S, Vaney, M.C, Rey, F.A. 登録日 2008-07-08 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283, 2008
2YRF	Crystal structure of 5-methylthioribose 1-phosphate isomerase from Bacillus subtilis complexed with sulfate ion 分子名称: Methylthioribose-1-phosphate isomerase, SULFATE ION 著者 Tamura, H, Inoue, T, Kai, Y, Matsumura, H. 登録日 2007-04-02 公開日 2008-01-22 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: Implications for catalytic mechanism Protein Sci., 17, 2008
3DCK	X-ray structure of D25N chemical analogue of HIV-1 protease complexed with ketomethylene isostere inhibitor 分子名称: (2S)-2-{[(2R,5S)-5-{[(2S,3S)-2-{[(2S,3R)-2-(acetylamino)-3-hydroxybutanoyl]amino}-3-methylpentanoyl]amino}-2-butyl-4-oxononanoyl]amino}-N~1~-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]pentanediamide, Chemical analogue HIV-1 protease 著者 Torbeev, V.Y, Mandal, K, Terechko, V.A, Kent, S.B.H. 登録日 2008-06-03 公開日 2008-08-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site Bioorg.Med.Chem.Lett., 18, 2008
3DS3	HIV-1 capsid C-terminal domain mutant (Y169A) in complex with an inhibitor of particle assembly (CAI) 分子名称: HIV-1 CAPSID PROTEIN, Peptide inhibitor of capsid assembly 著者 Igonet, S, Vaney, M.C, Rey, F.A. 登録日 2008-07-11 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283, 2008
3DS4	HIV-1 capsid C-terminal domain mutant (L211S) in complex with an inhibitor of particle assembly (CAI) 分子名称: HIV-1 CAPSID PROTEIN, Peptide inhibitor of capsid assembly 著者 Igonet, S, Vaney, M.C, Rey, F.A. 登録日 2008-07-11 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283, 2008
1OK4	Archaeal fructose 1,6-bisphosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I 著者 Lorentzen, E, Zwart, P, Stark, A, Hensel, R, Siebers, B, Pohl, E. 登録日 2003-07-17 公開日 2003-09-04 最終更新日 2025-10-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins. J. Biol. Chem., 278, 2003
2WIY	Cytochrome P450 XplA heme domain P21212 分子名称: 1,2-ETHANEDIOL, CYTOCHROME P450-LIKE PROTEIN XPLA, IMIDAZOLE, ... 著者 Sabbadin, F, Jackson, R, Bruce, N.C, Grogan, G. 登録日 2009-05-18 公開日 2009-08-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 The 1.5-A Structure of Xpla-Heme, an Unusual Cytochrome P450 Heme Domain that Catalyzes Reductive Biotransformation of Royal Demolition Explosive. J.Biol.Chem., 284, 2009
3TKG	crystal structure of HIV model protease precursor/saquinavir complex 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, GLYCEROL, ... 著者 Agniswamy, J, Sayer, J, Weber, I, Louis, J. 登録日 2011-08-26 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Terminal interface conformations modulate dimer stability prior to amino terminal autoprocessing of HIV-1 protease. Biochemistry, 51, 2012
3OT3	X-ray crystal structure of compound 22k bound to human Chk1 kinase domain 分子名称: 5-[(1R,3S)-3-aminocyclohexyl]-6-bromo-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine, Serine/threonine-protein kinase Chk1 著者 Fischmann, T.O. 登録日 2010-09-10 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach-Part 2. Bioorg.Med.Chem.Lett., 21, 2011
2HOT	Phage selected homeodomain bound to modified DNA 分子名称: 3-PROP-2-YN-1-YL-1,3-OXAZOLIDIN-2-ONE, 5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*CP*CP*GP*GP*A)-3', ... 著者 Feldman, M.E, Simon, M.D, Shokat, K.M. 登録日 2006-07-16 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure and properties of a re-engineered homeodomain protein-DNA interface. Acs Chem.Biol., 1, 2006
4H1T	X-RAY Structure of the Complex VchUPh with Phosphate ion at 1.92A Resolution. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Prokofev, I.I, Lashkov, A.A, Gabdoulkhakov, A.G, Sotnichenko, S.E, Betzel, C, Mikhailov, A.M. 登録日 2012-09-11 公開日 2013-09-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.924 Å) 主引用文献 X-RAY Structure of the Complex VchUPh with Phosphate ion at 1.92A Resolution. TO BE PUBLISHED
2HQ9	Crystal structure of a fad-binding protein (mll6688) from mesorhizobium loti at 1.95 A resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-07-18 公開日 2006-08-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of hypothetical protein (NP_107146.1) from MESORHIZOBIUM LOTI at 1.95 A resolution To be published
3OOM	Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00507 分子名称: 1,2-ETHANEDIOL, 1-{3-[6-(tetrahydro-2H-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone, Activin receptor type-1, ... 著者 Chaikuad, A, Sanvitale, C, Cooper, C, Mahajan, P, Daga, N, Petrie, K, Alfano, I, Gileadi, O, Fedorov, O, Allerston, C, Krojer, T, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2010-08-31 公開日 2010-10-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00507 To be Published

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