8AFX
 
 | | Single particle structure of Atg18-WT | | 分子名称: | Autophagy-related protein 18 | | 著者 | Mann, D, Fromm, S, Martinez-Sanchez, A, Gopaldass, N, Mayer, A, Sachse, C. | | 登録日 | 2022-07-18 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Atg18 oligomer organization in assembled tubes and on lipid membrane scaffolds.
Nat Commun, 14, 2023
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8BBF
 | | Structure of the IFT-A complex; IFT-A1 module | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, WD repeat-containing protein 19 | | 著者 | Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. | | 登録日 | 2022-10-12 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | IFT-A structure reveals carriages for membrane protein transport into cilia.
Cell, 185, 2022
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8BBG
 | | Structure of the IFT-A complex; anterograde IFT-A train model | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... | | 著者 | Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. | | 登録日 | 2022-10-12 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | IFT-A structure reveals carriages for membrane protein transport into cilia.
Cell, 185, 2022
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8BBE
 | | Structure of the IFT-A complex; IFT-A2 module | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, SNAP-tag,Tetratricopeptide repeat protein 21B, ... | | 著者 | Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. | | 登録日 | 2022-10-12 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | IFT-A structure reveals carriages for membrane protein transport into cilia.
Cell, 185, 2022
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8BD7
 | | IFTB1 subcomplex of anterograde Intraflagellar transport trains (Chlamydomonas reinhardtii) | | 分子名称: | Clusterin-associated protein 1, IFT54, IFT70, ... | | 著者 | Lacey, S.E, Foster, H.E, Pigino, G. | | 登録日 | 2022-10-18 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | | 主引用文献 | The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains.
Nat.Struct.Mol.Biol., 30, 2023
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8BDA
 | | IFTA complex in anterograde intraflagellar transport trains (Chlamydomonas reinhardtii) | | 分子名称: | Intraflagellar transport particle protein 140, Intraflagellar transport protein 121, Intraflagellar transport protein 122 homolog, ... | | 著者 | Lacey, S.E, Foster, H.E, Pigino, G. | | 登録日 | 2022-10-18 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (20.700001 Å) | | 主引用文献 | The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains.
Nat.Struct.Mol.Biol., 30, 2023
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8CLJ
 | | TFIIIC TauB-DNA dimer | | 分子名称: | General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... | | 著者 | Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. | | 登録日 | 2023-02-16 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
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8CLL
 | | Structural insights into human TFIIIC promoter recognition | | 分子名称: | General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... | | 著者 | Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. | | 登録日 | 2023-02-16 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
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8CLI
 | | TFIIIC TauB-DNA monomer | | 分子名称: | DNA (35-MER), General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, ... | | 著者 | Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. | | 登録日 | 2023-02-16 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
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6Q8I
 | | Nterminal domain of human SMU1 in complex with human REDmid | | 分子名称: | Protein Red, WD40 repeat-containing protein SMU1 | | 著者 | Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6QK7
 | | Elongator catalytic subcomplex Elp123 lobe | | 分子名称: | 5'-DEOXYADENOSINE, Elongator complex protein 1, Elongator complex protein 2, ... | | 著者 | Dauden, M.I, Jaciuk, M, Glatt, S. | | 登録日 | 2019-01-28 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis of tRNA recognition by the Elongator complex.
Sci Adv, 5, 2019
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6RMV
 | | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | | 分子名称: | GLYCEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Gruss, F, Oberwinkler, J, Ulens, C. | | 登録日 | 2019-05-07 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The structural basis for an on-off switch controlling G beta gamma-mediated inhibition of TRPM3 channels.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RLB
 | | Structure of the dynein-2 complex; tail domain | | 分子名称: | Cytoplasmic dynein 2 light intermediate chain 1, Dynein light chain 1, cytoplasmic, ... | | 著者 | Toropova, K, Zalyte, R, Mukhopadhyay, A.G, Mladenov, M, Carter, A.P, Roberts, A.J. | | 登録日 | 2019-05-01 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of the dynein-2 complex and its assembly with intraflagellar transport trains.
Nat.Struct.Mol.Biol., 26, 2019
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6Q8F
 | | Nterminal domain of human SMU1 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, WD40 repeat-containing protein SMU1 | | 著者 | Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6RLQ
 | | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882 | | 分子名称: | (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop entane-1,2-diol, Methylosome protein 50, Protein arginine N-methyltransferase 5 | | 著者 | Brown, D.G, Robinson, C.M, Pande, V. | | 登録日 | 2019-05-02 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
To Be Published
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6RLL
 | | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ44064146 | | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)-5-(1,8-diazaspiro[4.5]decan-1-ylmethyl)oxolane-3,4-diol, Methylosome protein 50, Protein arginine N-methyltransferase 5 | | 著者 | Brown, D.G, Robinson, C.M, Pande, V. | | 登録日 | 2019-05-02 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | A chemical probe for the methyl transferase PRMT5 with a novel
binding mode
To Be Published
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6S1L
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6S1R
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6S29
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6SB2
 | | cryo-EM structure of mTORC1 bound to active RagA/C GTPases | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ... | | 著者 | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | | 登録日 | 2019-07-18 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
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6SC2
 | | Structure of the dynein-2 complex; IFT-train bound model | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 2 light intermediate chain 1, ... | | 著者 | Toropova, K, Zalyte, R, Mukhopadhyay, A.G, Mladenov, M, Carter, A.P, Roberts, A.J. | | 登録日 | 2019-07-23 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the dynein-2 complex and its assembly with intraflagellar transport trains.
Nat.Struct.Mol.Biol., 26, 2019
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6U4Y
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6U62
 | | Raptor-Rag-Ragulator complex | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Rogala, K.B, Sabatini, D.M. | | 登録日 | 2019-08-29 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural basis for the docking of mTORC1 on the lysosomal surface.
Science, 366, 2019
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6UGH
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6V0N
 | | PRMT5 bound to PBM peptide from Riok1 | | 分子名称: | Methylosome protein 50, Protein arginine N-methyltransferase 5, Riok1 PBM peptide, ... | | 著者 | McMIllan, B.J, Raymond, D.D. | | 登録日 | 2019-11-19 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol.Cell, 81, 2021
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