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6U4Y

Crystal Structure of an EZH2-EED Complex in an Oligomeric State

Summary for 6U4Y
Entry DOI10.2210/pdb6u4y/pdb
DescriptorHistone-lysine N-methyltransferase EZH2, Polycomb protein EED (2 entities in total)
Functional Keywordsmethyltransferase, transferase, transcription
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight203658.36
Authors
Jiao, L.,Liu, X. (deposition date: 2019-08-26, release date: 2020-07-08, Last modification date: 2024-03-13)
Primary citationJiao, L.,Shubbar, M.,Yang, X.,Zhang, Q.,Chen, S.,Wu, Q.,Chen, Z.,Rizo, J.,Liu, X.
A partially disordered region connects gene repression and activation functions of EZH2.
Proc.Natl.Acad.Sci.USA, 117:16992-17002, 2020
Cited by
PubMed: 32631994
DOI: 10.1073/pnas.1914866117
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.91 Å)
Structure validation

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