6U4Y

Crystal Structure of an EZH2-EED Complex in an Oligomeric State

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006338	biological_process	chromatin remodeling
A	0042054	molecular_function	histone methyltransferase activity
A	0046976	molecular_function	histone H3K27 methyltransferase activity
B	0006338	biological_process	chromatin remodeling
B	0042054	molecular_function	histone methyltransferase activity
B	0046976	molecular_function	histone H3K27 methyltransferase activity
C	0006338	biological_process	chromatin remodeling
C	0042054	molecular_function	histone methyltransferase activity
C	0046976	molecular_function	histone H3K27 methyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSVskDhALRLWNI

Chain	Residue	Details
D	LEU206-ILE220

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:20974918

Chain	Residue	Details
D	LYS197
D	LYS268
D	LYS284
E	LYS197
E	LYS268
E	LYS284
F	LYS197
F	LYS268
F	LYS284

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site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER76
B	SER76
C	SER76

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000269|PubMed:24474760

Chain	Residue	Details
A	SER75
B	SER75
C	SER75

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