7LKF

WT Chicken Scap L1-L7 / Fab 4G10 complex focused refinement

Summary for 7LKF

Entry DOI	10.2210/pdb7lkf/pdb
EMDB information	23405
Descriptor	Sterol regulatory element-binding protein cleavage-activating protein, 4G10 heavy chain, 4G10 light chain, ... (4 entities in total)
Functional Keywords	cholesterol, lipid binding protein, srebp
Biological source	Gallus gallus (Chicken) More
Total number of polymer chains	3
Total formula weight	197246.83
Authors	Kober, D.L.,Radhakrishnan, A.,Goldstein, J.L.,Brown, M.S.,Clark, L.D.,Bai, X.-C.,Rosenbaum, D.M. (deposition date: 2021-02-02, release date: 2021-06-30, Last modification date: 2021-07-28)
Primary citation	Kober, D.L.,Radhakrishnan, A.,Goldstein, J.L.,Brown, M.S.,Clark, L.D.,Bai, X.C.,Rosenbaum, D.M. Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing. Cell, 184:3689-, 2021 Cited by PubMed: 34139175 DOI: 10.1016/j.cell.2021.05.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation