7A57
 
 | | La Crosse Virus Envelope Glycoprotein Gc W1066H Mutant Fusion Domains in Postfusion Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein | | 著者 | Hellert, J, Guardado-Calvo, P, Rey, F.A. | | 登録日 | 2020-08-20 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.155 Å) | | 主引用文献 | Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.
Cell Rep, 42, 2023
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7A5A
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7A59
 | | Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in Postfusion Conformation (Orthorhombic Crystal Form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Envelopment polyprotein, ... | | 著者 | Hellert, J, Guardado-Calvo, P, Rey, F.A. | | 登録日 | 2020-08-20 | | 公開日 | 2021-10-06 | | 最終更新日 | 2022-04-20 | | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | | 主引用文献 | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
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4Z8A
 | | SH3-III of Drosophila Rim-binding protein bound to a Cacophony derived peptide | | 分子名称: | RIM-binding protein, isoform F, Voltage-dependent calcium channel type A subunit alpha-1 | | 著者 | Driller, J.H, Holton, N, Siebert, M, Boehme, A.M, Wahl, M.C, Sigrist, S.J, Loll, B. | | 登録日 | 2015-04-08 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.759 Å) | | 主引用文献 | A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Elife, 4, 2015
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3DVH
 | | LC8 Point mutant K36P | | 分子名称: | Dynein light chain 1, cytoplasmic | | 著者 | Lightcap, C.M, Williams, J.C. | | 登録日 | 2008-07-18 | | 公開日 | 2009-01-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
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3DVP
 | | Pak1 peptide bound LC8 | | 分子名称: | Dynein light chain 1, cytoplasmic, P21 activated Kinase peptide | | 著者 | Lightcap, C.M, Williams, J.C. | | 登録日 | 2008-07-18 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
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4Z88
 | | SH3-II of Drosophila Rim-binding protein with Aplip1 peptide | | 分子名称: | JNK-interacting protein 1, PHOSPHATE ION, RIM-binding protein, ... | | 著者 | Driller, J.H, Holton, N, Siebert, M, Boehme, M.A, Wahl, M.C, Sigrist, S.J, Loll, B. | | 登録日 | 2015-04-08 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Elife, 4, 2015
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4ZLR
 | | Structure of the Brat-NHL domain bound to consensus RNA motif | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brain tumor protein, PENTAETHYLENE GLYCOL, ... | | 著者 | Jakob, L, Treiber, N, Treiber, T, Stotz, M, Loedige, I, Meister, G. | | 登録日 | 2015-05-01 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation.
Cell Rep, 13, 2015
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6ZBA
 | | Crystal structure of PDE4D2 in complex with inhibitor LEO39652 | | 分子名称: | 1,2-ETHANEDIOL, 2-methylpropyl 1-[8-methoxy-5-(1-oxidanylidene-3~{H}-2-benzofuran-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropane-1-carboxylate, DIMETHYL SULFOXIDE, ... | | 著者 | Akutsu, M, Hakansson, M, Welin, M, Svensson, A, Logan, D.T, Sorensen, M.D. | | 登録日 | 2020-06-08 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery and Early Clinical Development of Isobutyl 1-[8-Methoxy-5-(1-oxo-3 H -isobenzofuran-5-yl)-[1,2,4]triazolo[1,5- a ]pyridin-2-yl]cyclopropanecarboxylate (LEO 39652), a Novel "Dual-Soft" PDE4 Inhibitor for Topical Treatment of Atopic Dermatitis.
J.Med.Chem., 63, 2020
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7A3O
 | | Crystal structure of dengue 1 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10 | | 分子名称: | Core protein, GLYCEROL, SULFATE ION, ... | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7A3R
 | | Crystal structure of dengue 1 virus envelope glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Core protein, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7A3N
 | | Crystal structure of Zika virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C10 | | 分子名称: | CALCIUM ION, Core protein, EDE1 C10 Fab | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7A3T
 | | Crystal structure of dengue 3 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C8 | | 分子名称: | Core protein, EDE1 C8 antibody Fab fragment, GLYCEROL, ... | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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4I7C
 | | Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ... | | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | | 登録日 | 2012-11-30 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-based design of covalent siah inhibitors.
Chem.Biol., 20, 2013
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7A3U
 | | Crystal structure of Zika virus envelope glycoprotein in complex with the divalent F(ab')2 fragment of the broadly neutralizing human antibody EDE1 C10 | | 分子名称: | EDE1 C10 antibody divalent F(ab')2 fragment, EDE1 C10 divalent F(ab')2 fragment, Envelope protein | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7A3P
 | | Crystal structure of dengue 3 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Single Chain Variable Fragment | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7A3S
 | | Crystal structure of dengue 3 virus envelope glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SULFATE ION | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Navarro-Sanchez, E, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7A3Q
 | | Crystal structure of dengue 4 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10 | | 分子名称: | (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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7AAF
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7AAO
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4I7D
 | | Siah1 bound to synthetic peptide (ACE)KLRPVAMVRP(PRK)VR | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ... | | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | | 登録日 | 2012-11-30 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based design of covalent siah inhibitors.
Chem.Biol., 20, 2013
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4IMI
 | | Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72. | | 分子名称: | CG14216, CTD, PHOSPHATE ION, ... | | 著者 | Luo, Y, Yogesha, S.D, Zhang, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2013-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72.
Acs Chem.Biol., 8, 2013
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7AZB
 | | Structure of DDR2 DS domain in complex with VHH | | 分子名称: | Discoidin domain-containing receptor 2, VHH | | 著者 | Talagas, A, Nawrotek, A, Arrial, A, Vuillard, L.M, Miallau, L. | | 登録日 | 2020-11-16 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structure of DDR2 DS domain in complex with VHH
To Be Published
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3PC4
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3PC2
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