7A5A

Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in Postfusion Conformation (Monoclinic Crystal Form)

This is a non-PDB format compatible entry.

Summary for 7A5A

• Entry DOI: 10.2210/pdb7a5a/pdb
• Descriptor: Envelopment polyprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION (3 entities in total)
• Functional Keywords: virus entry, class ii membrane fusion protein, viral protein
• Biological source: Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV)
• Total number of polymer chains: 6
• Total formula weight: 361909.83

Authors

Hellert, J.,Guardado-Calvo, P.,Rey, F.A. (deposition date: 2020-08-20, release date: 2021-10-06, Last modification date: 2024-01-31)

• Primary citation: Mishra, A.K.,Hellert, J.,Freitas, N.,Guardado-Calvo, P.,Haouz, A.,Fels, J.M.,Maurer, D.P.,Abelson, D.M.,Bornholdt, Z.A.,Walker, L.M.,Chandran, K.,Cosset, F.L.,McLellan, J.S.,Rey, F.A.; Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.; Science, 375:104-109, 2022; PubMed: 34793197; DOI: 10.1126/science.abl6502

Experimental method

X-RAY DIFFRACTION (2.989 Å)