3PC4

Full length structure of cystathionine beta-synthase from Drosophila in complex with serine

Summary for 3PC4

Entry DOI	10.2210/pdb3pc4/pdb
Related	3PC2 3PC3
Descriptor	CG1753, isoform A, PROTOPORPHYRIN IX CONTAINING FE, (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, ... (5 entities in total)
Functional Keywords	cbs, synthase, plp, heme, carbanion, lyase
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	1
Total formula weight	58443.51
Authors	Koutmos, M.,Smith, J.L. (deposition date: 2010-10-21, release date: 2010-12-01, Last modification date: 2023-09-06)
Primary citation	Koutmos, M.,Kabil, O.,Smith, J.L.,Banerjee, R. Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proc.Natl.Acad.Sci.USA, 107:20958-20963, 2010 Cited by PubMed: 21081698 DOI: 10.1073/pnas.1011448107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation