PDB: 10530 件ウェブページステータス検索Chemie searchBIRD

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3V5N	The crystal structure of oxidoreductase from Sinorhizobium meliloti 分子名称: Oxidoreductase 著者 Zhang, Z, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2011-12-16 公開日 2012-01-04 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 The crystal structure of oxidoreductase from Sinorhizobium meliloti To be Published
8JUD	Crystal structure of human MMP-7 in complex with inhibitor 分子名称: CALCIUM ION, Matrilysin, Peptide Inhibitor, ... 著者 Kamitani, M, Abe-Sato, K, Oka, Y. 登録日 2023-06-26 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J.Med.Chem., 66, 2023
8JUF	Crystal structure of human MMP-7 in complex with inhibitor 分子名称: CALCIUM ION, Matrilysin, Peptide Inhibitor, ... 著者 Kamitani, M, Abe-Sato, K, Oka, Y. 登録日 2023-06-26 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J.Med.Chem., 66, 2023
8JUG	Crystal structure of human MMP-7 in complex with inhibitor 分子名称: CALCIUM ION, Matrilysin, Peptide Inhibitor, ... 著者 Kamitani, M, Abe-Sato, K, Oka, Y. 登録日 2023-06-26 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J.Med.Chem., 66, 2023
7OO5	Crystal structure of the lignin peroxidase (ApeLiP) from Agrocybe pediades 分子名称: CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... 著者 Romero, A, Ruiz-Duenas, F.J. 登録日 2021-05-26 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Agaricales Mushroom Lignin Peroxidase: From Structure-Function to Degradative Capabilities. Antioxidants, 10, 2021
6WKU	Twelve Chloride Ions Drive Assembly of Human alpha345 Collagen IV NC1 domain 分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... 著者 Boudko, S.P, Hudson, B.G. 登録日 2020-04-17 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Collagen IV alpha 345 dysfunction in glomerular basement membrane diseases. II. Crystal structure of the alpha 345 hexamer. J.Biol.Chem., 296, 2021
3V8B	Crystal Structure of a 3-ketoacyl-ACP reductase from Sinorhizobium meliloti 1021 分子名称: Putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier protein] reductase 著者 Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2011-12-22 公開日 2012-01-11 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of a 3-ketoacyl-ACP reductase from Sinorhizobium meliloti 1021 To be Published
8OPU	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Sulfamethoxazole (Fragment-B-E1) 分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ... 著者 Dalwani, S, Wierenga, R.K, Venkatesan, R. 登録日 2023-04-10 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
3ET2	Structure of PPARdelta with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid 分子名称: 1-BUTANOL, 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor delta 著者 Zhang, K.Y.J, Wang, W. 登録日 2008-10-06 公開日 2009-02-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009
6EQX	X-ray structure of the proprotein convertase furin bound with the competitive inhibitor Arg-Arg-Arg-Val-Arg-Amba 分子名称: Arg-Arg-Arg-Val-Arg-00S, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Than, M.E. 登録日 2017-10-16 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.994 Å) 主引用文献 X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket. Biochemistry, 57, 2018
6ZTK	Crystal structure of Mialostatin, a gut cystatin from the hard tick Ixodes ricinus 分子名称: FRAGMENT OF TRITON X-100, Mialostatin, SULFATE ION 著者 Busa, M, Rezacova, P, Mares, M. 登録日 2020-07-20 公開日 2021-06-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion. Int J Mol Sci, 22, 2021
4QB5	Crystal structure of a glyoxalase/bleomycin resistance protein from Albidiferax ferrireducens T118 分子名称: 1,2-ETHANEDIOL, Glyoxalase/bleomycin resistance protein/dioxygenase, SULFATE ION 著者 Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2014-05-06 公開日 2014-07-23 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of a glyoxalase/bleomycin resistance protein from Albidiferax ferrireducens T118 To be Published
3ET1	Structure of PPARalpha with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid 分子名称: 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor alpha, Steroid receptor coactivator 1 著者 Zhang, K.Y.J, Wang, W. 登録日 2008-10-06 公開日 2009-02-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009
8K4Z	Crystal structure of human MMP-7 in complex with inhibitor 分子名称: CALCIUM ION, CHLORIDE ION, IODIDE ION, ... 著者 Kamitani, M, Mima, M, Oka, Y. 登録日 2023-07-20 公開日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of TP0628103: A Selective MMP-7 Inhibitor Based on the Mitigation of OATP Substrate Recognition through Isoelectric Point Shift Strategy To Be Published
6EQW	X-ray structure of the proprotein convertase furin bound with the competitive inhibitor 4-aminomethyl-phenylacetyl-Arg-Val-Arg-Amba 分子名称: AMA-ARG-TBG-ARG-00S, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Than, M.E. 登録日 2017-10-16 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.994 Å) 主引用文献 X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket. Biochemistry, 57, 2018
6EQV	X-ray structure of the proprotein convertase furin bound with the competitive inhibitor Phac-Cit-Val-Arg-Amba 分子名称: CALCIUM ION, CHLORIDE ION, Furin, ... 著者 Dahms, S.O, Than, M.E. 登録日 2017-10-16 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket. Biochemistry, 57, 2018
7PUU	Crystal structure of carbonic anhydrase XII with methyl 4-chloro-2-cyclohexylsulfanyl-5-sulfamoylbenzoate 分子名称: 1,2-ETHANEDIOL, Carbonic anhydrase 12, ZINC ION, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2021-09-30 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci, 23, 2021
7PUW	Crystal structure of carbonic anhydrase XII with methyl 2-chloro-4-[(2-phenylethyl)sulfanyl]-5-sulfamoylbenzoate 分子名称: 1,2-ETHANEDIOL, Carbonic anhydrase 12, ZINC ION, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2021-09-30 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci, 23, 2021
7Q0C	Mimic carbonic anhydrase IX in complex with Methyl 2-chloro-4-(cyclohexylsulfanyl)-5-sulfamoylbenzoate 分子名称: ACETATE ION, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Paketuryte-Latve, V, Smirnov, A, Manakova, E, Grazulis, S. 登録日 2021-10-14 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci, 23, 2021
1JLB	CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE 分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 RT A-chain, HIV-1 RT B-chain 著者 Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. 登録日 2001-07-16 公開日 2001-10-03 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J.Mol.Biol., 312, 2001
7AWG	Crystal structure of human butyrylcholinesterase in complex with (2-((1-(benzenesulfonyl)-1H-indol-4-yl)oxy)ethyl)(benzyl)amine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Brazzolotto, X, Wichur, T, Wieckowska, A. 登録日 2020-11-08 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT 6 R antagonists with beta-amyloid anti-aggregation properties. Eur.J.Med.Chem., 225, 2021
7AWH	Crystal structure of human butyrylcholinesterase in complex with tert-butyl 3-(((2-((1-(benzenesulfonyl)-1H-indol-4-yl)oxy)ethyl)amino)methyl)piperidine-1-carboxylate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Brazzolotto, X, Wichur, T, Wieckowska, A. 登録日 2020-11-08 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT 6 R antagonists with beta-amyloid anti-aggregation properties. Eur.J.Med.Chem., 225, 2021
6MT7	Phlebotomus duboscqi salivary D7 protein, selenomethionine derivative 分子名称: 26.7 kDa salivary protein, FRAGMENT OF TRITON X-100 著者 Andersen, J.F, Jablonka, W. 登録日 2018-10-19 公開日 2019-04-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Functional and structural similarities of D7 proteins in the independently-evolved salivary secretions of sand flies and mosquitoes. Sci Rep, 9, 2019
6MTF	D7 protein from Phlebotomus duboscqi, native 分子名称: 26.7 kDa salivary protein, FRAGMENT OF TRITON X-100 著者 Andersen, J.F, Jablonka, W. 登録日 2018-10-19 公開日 2019-04-10 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Functional and structural similarities of D7 proteins in the independently-evolved salivary secretions of sand flies and mosquitoes. Sci Rep, 9, 2019
1KN5	SOLUTION STRUCTURE OF ARID DOMAIN OF ADR6 FROM SACCHAROMYCES CEREVISIAE 分子名称: Transcription regulatory protein ADR6 著者 Tu, X, Wu, J, Xu, Y, Shi, Y. 登録日 2001-12-18 公開日 2002-07-17 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain. J.Biomol.Nmr, 21, 2001

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