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2EA2
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h-MetAP2 complexed with A773812
分子名称: 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.H.
登録日2007-01-30
公開日2008-02-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids
Bioorg.Med.Chem.Lett., 17, 2007
4OZ5
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BU of 4oz5 by Molmil
Bacillus subtilis HmoB
分子名称: Bacillus subtilis HmoB, PROTOPORPHYRIN IX CONTAINING FE
著者Choe, J, Park, S.
登録日2014-02-13
公開日2015-02-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Bacillus subtilis HmoB
To Be Published
3S3R
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BU of 3s3r by Molmil
Structure of cathepsin B1 from Schistosoma mansoni in complex with K11777 inhibitor
分子名称: Cathepsin B-like peptidase (C01 family), Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide
著者Rezacova, P, Jilkova, A, Brynda, J, Horn, M, Mares, M.
登録日2011-05-18
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni.
J.Biol.Chem., 286, 2011
3T67
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BU of 3t67 by Molmil
Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
分子名称: CATECHOL, FE (III) ION, GLYCEROL, ...
著者Purpero, V.M, Lipscomb, J.D.
登録日2011-07-28
公開日2012-08-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
To be Published
4POO
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BU of 4poo by Molmil
The crystal structure of Bacillus subtilis YtqB in complex with SAM
分子名称: Putative RNA methylase, S-ADENOSYLMETHIONINE
著者Park, S.C, Song, W.S, Yoon, S.I.
登録日2014-02-26
公開日2014-04-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis
Biochem.Biophys.Res.Commun., 446, 2014
3SZ9
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BU of 3sz9 by Molmil
Crystal structure of human ALDH2 modified with the beta-elimination product of Aldi-3; 1-(4-ethylbenzene)prop-2-en-1-one
分子名称: 1,2-ETHANEDIOL, 1-(4-ethylphenyl)propan-1-one, Aldehyde dehydrogenase, ...
著者Perez-Miller, S, Hurley, T.D.
登録日2011-07-18
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
J.Biol.Chem., 286, 2011
3PR2
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BU of 3pr2 by Molmil
Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site
分子名称: (Z)-N-[(1E)-1-carboxy-2-(2,3-dihydro-1H-indol-1-yl)ethylidene]{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methanaminium, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ...
著者Lai, J, Niks, D, Wang, Y, Domratcheva, T, Barends, T.R.M, Schwarz, F, Olsen, R.A, Elliott, D.W, Fatmi, M.Q, Chang, C.A, Schlichting, I, Dunn, M.F, Mueller, L.J.
登録日2010-11-29
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献X-ray and NMR Crystallography in an Enzyme Active Site: The Indoline Quinonoid Intermediate in Tryptophan Synthase.
J.Am.Chem.Soc., 133, 2011
1D2V
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BU of 1d2v by Molmil
CRYSTAL STRUCTURE OF BROMIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BROMIDE ION, ...
著者Fiedler, T.J, Davey, C.A, Fenna, R.E.
登録日1999-09-28
公開日2000-04-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution.
J.Biol.Chem., 275, 2000
1D5L
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BU of 1d5l by Molmil
CRYSTAL STRUCTURE OF CYANIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
著者Fiedler, T.J, Davey, C.A, Fenna, R.E.
登録日1999-10-07
公開日2001-12-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
Biochemistry, 40, 2001
1CXP
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BU of 1cxp by Molmil
CRYOGENIC CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE ISOFORM C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
著者Fiedler, T.J, Fenna, R.E.
登録日1999-08-30
公開日2000-04-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution.
J.Biol.Chem., 275, 2000
4PON
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BU of 4pon by Molmil
The crystal structure of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis
分子名称: Putative RNA methylase
著者Park, S.C, Song, W.S, Yoon, S.I.
登録日2014-02-26
公開日2014-04-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis
Biochem.Biophys.Res.Commun., 446, 2014
2ZED
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BU of 2zed by Molmil
Crystal structure of the human glutaminyl cyclase mutant S160A at 1.7 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-12
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEH
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BU of 2zeh by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201Q at 1.8 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-12
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
1I84
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BU of 1i84 by Molmil
CRYO-EM STRUCTURE OF THE HEAVY MEROMYOSIN SUBFRAGMENT OF CHICKEN GIZZARD SMOOTH MUSCLE MYOSIN WITH REGULATORY LIGHT CHAIN IN THE DEPHOSPHORYLATED STATE. ONLY C ALPHAS PROVIDED FOR REGULATORY LIGHT CHAIN. ONLY BACKBONE ATOMS PROVIDED FOR S2 FRAGMENT.
分子名称: SMOOTH MUSCLE MYOSIN ESSENTIAL LIGHT CHAIN, SMOOTH MUSCLE MYOSIN HEAVY CHAIN, SMOOTH MUSCLE MYOSIN REGULATORY LIGHT CHAIN
著者Wendt, T, Taylor, D, Trybus, K.M, Taylor, K.
登録日2001-03-12
公開日2001-03-28
最終更新日2022-12-21
実験手法ELECTRON CRYSTALLOGRAPHY (20 Å)
主引用文献Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2.
Proc.Natl.Acad.Sci.USA, 98, 2001
7Q6J
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BU of 7q6j by Molmil
Crystal structure of the human GDAP1 CMT2 mutant-H123R
分子名称: DI(HYDROXYETHYL)ETHER, Ganglioside-induced differentiation-associated protein 1
著者Sutinen, A, Kursula, P.
登録日2021-11-08
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1.
Febs Open Bio, 12, 2022
2ZEO
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BU of 2zeo by Molmil
Crystal structure of the human glutaminyl cyclase mutant D305E at 1.66 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-13
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEF
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BU of 2zef by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201D at 1.67 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-12
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEL
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BU of 2zel by Molmil
Crystal structure of the human glutaminyl cyclase mutant D248A at 1.97 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-13
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
6F3X
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BU of 6f3x by Molmil
Backbone structure of Des-Arg10-Kallidin (DAKD) peptide in frozen DDM/CHS detergent micelle solution determined by DNP-enhanced MAS SSNMR
分子名称: Kininogen-1
著者Mao, J, Kuenze, G, Joedicke, L, Meiler, J, Michel, H, Glaubitz, C.
登録日2017-11-29
公開日2018-01-10
最終更新日2024-06-19
実験手法SOLID-STATE NMR
主引用文献The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.
Nat. Chem. Biol., 14, 2018
6ZMA
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BU of 6zma by Molmil
Structure of the tRNA-Monooxygenase enzyme MiaE frozen under 140 bar of krypton using the soak and freeze methodology
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Carpentier, P, Atta, M.
登録日2020-07-02
公開日2020-09-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural, biochemical and functional analyses of tRNA-monooxygenase enzyme MiaE from Pseudomonas putida provide insights into tRNA/MiaE interaction.
Nucleic Acids Res., 48, 2020
7Q6K
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BU of 7q6k by Molmil
Crystal structure of the human GDAP1 CMT2 mutant-R120W
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Sutinen, A, Kursula, P.
登録日2021-11-08
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1.
Febs Open Bio, 12, 2022
2ZEG
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BU of 2zeg by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201L at 2.08 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, IMIDAZOLE, SULFATE ION, ...
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-12
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEM
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BU of 2zem by Molmil
Crystal structure of the human glutaminyl cyclase mutant D248Q at 2.18 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-13
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEP
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BU of 2zep by Molmil
Crystal structure of the human glutaminyl cyclase mutant H319L at 2.1 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-13
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEE
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BU of 2zee by Molmil
Crystal structure of the human glutaminyl cyclase mutant S160G at 1.99 angstrom resolution
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
登録日2007-12-12
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008

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