PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4JR0	Human procaspase-3 bound to Ac-DEVD-CMK 分子名称: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-3 著者 Thomsen, N.D, Wells, J.A. 登録日 2013-03-20 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4JRH	Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P43) at 2.2 Angstrom 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION 著者 Hou, J, Chruszcz, M, Shabalin, I.G, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-03-21 公開日 2013-04-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献
4JLH	HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor 分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, HIV-1 Integrase catalytic core domain, SULFATE ION 著者 Feng, L, Kvaratskhelia, M. 登録日 2013-03-12 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors. J.Biol.Chem., 288, 2013
4JUT	Crystal structure of a mutant fragment of Human HSPB6 分子名称: GLYCEROL, Heat shock protein beta-6 著者 Weeks, S.D, Baranova, E.V, Beelen, S, Heirbaut, M, Gusev, N.B, Strelkov, S.V. 登録日 2013-03-25 公開日 2014-02-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.196 Å) 主引用文献 Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6. J.Struct.Biol., 185, 2014
4JWG	Crystal structure of spTrm10(74) 分子名称: ACETIC ACID, tRNA (guanine(9)-N1)-methyltransferase 著者 Yan, W, Shao, Z. 登録日 2013-03-27 公開日 2013-10-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate. Nucleic Acids Res., 42, 2014
4JQU	Crystal structure of Ubc7p in complex with the U7BR of Cue1p 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... 著者 Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. 登録日 2013-03-20 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50, 2013
4JRC	Distal Stem I region from G. kaustophilus glyQS T box RNA 分子名称: Distal Stem I region of the glyQS T box leader RNA, MAGNESIUM ION 著者 Grigg, J.C, Ke, A. 登録日 2013-03-21 公開日 2013-04-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.673 Å) 主引用文献 T box RNA decodes both the information content and geometry of tRNA to affect gene expression. Proc.Natl.Acad.Sci.USA, 110, 2013
4KAL	Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid 分子名称: ADENOSINE, DIMETHYL SULFOXIDE, POTASSIUM ION, ... 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-04-22 公開日 2013-05-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid To be Published
4KAG	Crystal structure analysis of a single amino acid deletion mutation in EGFP 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... 著者 Arpino, J.A.J, Rizkallah, P.J. 登録日 2013-04-22 公開日 2014-08-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallogr.,Sect.D, 70, 2014
4KCE	Crystal structure of the mitochondrial peroxiredoxin from Leishmania braziliensis in the dimeric form 分子名称: Peroxidoxin 著者 Souza, T.A.C.B, Morais, M.A.B, Giuseppe, P.O, Murakami, M.T. 登録日 2013-04-24 公開日 2014-05-14 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal structure of the mitochondrial peroxiredoxin from Leishmania braziliensis in the dimeric form To be Published
4KG4	Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain (E198Q mutation) 分子名称: mRNA-decapping enzyme subunit 2 著者 Aglietti, R.A, Floor, S.N, Gross, J.D. 登録日 2013-04-28 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2. Structure, 21, 2013
4KK4	YwlE arginine phosphatase - C7S mutant with phosphorylated active site serine 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
4KHR	HCV NS5B GT1A C316Y with GSK5852 分子名称: NS5B RNA-dependent RNA polymerase, SULFATE ION, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic acid 著者 Williams, S.P, Kahler, K.M, Shotwell, J.B. 登録日 2013-05-01 公開日 2013-05-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J.Med.Chem., 57, 2014
4KMA	Crystal structure of Drosophila Suppressor of Fused 分子名称: GM14141p 著者 Zhang, Y, Qi, X, Zhang, Z, Wu, G. 登録日 2013-05-08 公開日 2013-11-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun, 4, 2013
4KK7	Structure of EccB1 from the type VII (ESX-1) secretion system of Mycobacterium tuberculosis. 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ESX-1 secretion system protein eccB1, GLYCEROL, ... 著者 Korotkov, K.V, Evans, T.J. 登録日 2013-05-05 公開日 2013-06-19 最終更新日 2016-03-23 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
4KNI	Crystal structure of human carbonic anhydrase isozyme II with 2-Chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2013-05-10 公開日 2013-11-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII Bioorg.Med.Chem., 21, 2013
4WIP	DIX domain of human Dvl2 分子名称: PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2 著者 Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W. 登録日 2014-09-26 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.691 Å) 主引用文献 Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization. Nat Commun, 6, 2015
4KNC	Structural and functional characterization of Pseudomonas aeruginosa AlgX 分子名称: Alginate biosynthesis protein AlgX 著者 Riley, L.M, Weadge, J.T, Baker, P, Robinson, H, Codee, J.D.C, Tipton, P.A, Ohman, D.E, Howell, P.L. 登録日 2013-05-09 公開日 2013-06-26 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.141 Å) 主引用文献 Structural and Functional Characterization of Pseudomonas aeruginosa AlgX: ROLE OF AlgX IN ALGINATE ACETYLATION. J.Biol.Chem., 288, 2013
4KQF	Crystal structure of CobT E174A complexed with adenine 分子名称: 1,2-ETHANEDIOL, ADENINE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, ... 著者 Chan, C.H, Newmister, S.A, Taylor, K.C, Claas, K.R, Rayment, I, Escalante-Semerena, J.C. 登録日 2013-05-15 公開日 2014-03-12 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica. Biochim.Biophys.Acta, 1840, 2014
4KR8	Salmonella typhi OmpF complex with Daunomycin 分子名称: DAUNOMYCIN, Outer membrane protein F 著者 Madhuranayaki, T, Balasubramaniam, D, Krishnaswamy, S. 登録日 2013-05-16 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Salmonella typhi OmpF complex with Daunomycin To be published
4KRP	Nanobody/VHH domain 9G8 in complex with the extracellular region of EGFR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab heavy chain, ... 著者 Ferguson, K.M, Schmitz, K.R. 登録日 2013-05-16 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.823 Å) 主引用文献 Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains. Structure, 21, 2013
4K1F	Crystal structure of reduced tryparedoxin peroxidase from leishmania major at 2.34 A resolution 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Ilari, A, Fiorillo, A, Di Chiaro, F. 登録日 2013-04-05 公開日 2014-04-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking Sci Rep, 5, 2015
4K2M	Crystal structure of ntda from bacillus subtilis in complex with the plp external aldimine adduct with kanosamine-6-phosphate 分子名称: 1,2-ETHANEDIOL, 3-deoxy-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-O-phosphono-alpha-D-gluco pyranose, ACETATE ION, ... 著者 Van Straaten, K.E, Palmer, D.R.J, Sanders, D.A.R. 登録日 2013-04-09 公開日 2013-10-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases. J.Biol.Chem., 288, 2013
4K2X	OxyS anhydrotetracycline hydroxylase from Streptomyces rimosus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Polyketide oxygenase/hydroxylase 著者 Wang, P, Sawaya, M.R, Tang, Y. 登録日 2013-04-09 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis. J.Am.Chem.Soc., 135, 2013
4E28	Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor 分子名称: 2-{(2Z,5S)-4-hydroxy-2-[(2E)-(2-hydroxybenzylidene)hydrazinylidene]-2,5-dihydro-1,3-thiazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide, 2-{(5S)-2-[(2E)-2-(2-hydroxybenzylidene)hydrazinyl]-4-oxo-4,5-dihydro-1,3-thiazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide, SULFATE ION, ... 著者 Tochowicz, A, Finer-Moore, J, Stroud, R.M, Costi, M.P. 登録日 2012-03-07 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase. J.Med.Chem., 55, 2012

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