4KRP

Nanobody/VHH domain 9G8 in complex with the extracellular region of EGFR

Summary for 4KRP

• Entry DOI: 10.2210/pdb4krp/pdb
• Related: 4KRL 4KRM 4KRN 4KRO
• Descriptor: Epidermal growth factor receptor, Nanobody/VHH domain 9G8, Cetuximab light chain, ... (7 entities in total)
• Functional Keywords: cell surface receptor, glycoprotein, nanobody, vhh domain, camelid vh domain, antibody, antigen, antibody complex, transferase-immune system complex, transferase/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 133015.09

Authors

Ferguson, K.M.,Schmitz, K.R. (deposition date: 2013-05-16, release date: 2013-08-28, Last modification date: 2023-09-20)

• Primary citation: Schmitz, K.R.,Bagchi, A.,Roovers, R.C.,van Bergen En Henegouwen, P.M.P.,Ferguson, K.M.; Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains.; Structure, 21:1214-1224, 2013; PubMed: 23791944; DOI: 10.1016/j.str.2013.05.008

Experimental method

X-RAY DIFFRACTION (2.823 Å)