PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

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3K1R	Structure of harmonin NPDZ1 in complex with the SAM-PBM of Sans 分子名称: Harmonin, Usher syndrome type-1G protein 著者 Pan, L, Yan, J, Zhang, M. 登録日 2009-09-28 公開日 2010-01-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins Proc.Natl.Acad.Sci.USA, 107, 2010
5XGV	The structure of Diels-Alderase PyrE3 in the biosynthetic pathway of pyrroindomycins 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PyrE3 著者 Pan, L, Gong, Y, Guo, Y. 登録日 2017-04-18 公開日 2018-04-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis. Cell Chem Biol, 25, 2018
5ZFL	Crystal structure of beta-lactamase PenP mutant E166Y 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase 著者 Pan, X, Zhao, Y. 登録日 2018-03-06 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10, 2020
5ZG6	Crystal structure of beta-lactamase PenP mutant-E166Y in complex with cephaloridine as "post-acylation" intermediate 分子名称: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase 著者 Pan, X, Zhao, Y. 登録日 2018-03-07 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10, 2020
5ZFT	Crystal structure of beta-lactamase PenP mutant-E166Y in complex with cephaloridine as "pre-deacylation" intermediate 分子名称: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase 著者 Pan, X, Zhao, Y. 登録日 2018-03-07 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis. Sci Rep, 10, 2020
7KFV	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody C1A-B12 Fab, Spike glycoprotein, ... 著者 Pan, J, Abraham, J, Clark, L, Clark, S. 登録日 2020-10-15 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFY	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of human antibody C1A-F10 Fab, ... 著者 Pan, J, Abraham, J, Clark, L, Clark, S. 登録日 2020-10-15 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.157 Å) 主引用文献 Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
7KFW	Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of antibody C1A-B3 Fab, ... 著者 Pan, J, Abraham, J, Clark, L, Clark, S. 登録日 2020-10-15 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.792 Å) 主引用文献 Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
8E83	Structure of 2-hydroxyisoflavanone synthase from Medicago truncatula 分子名称: Isoflavone synthase 1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Pan, H, Wang, X. 登録日 2022-08-25 公開日 2022-11-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The protein conformational basis of isoflavone biosynthesis. Commun Biol, 5, 2022
8EA2	Structure of 2-hydroxyisoflavanone dehydratase from Pueraria lobate 分子名称: 2-hydroxyisoflavanone dehydratase 著者 Pan, H, Wang, X. 登録日 2022-08-27 公開日 2022-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 The protein conformational basis of isoflavone biosynthesis. Commun Biol, 5, 2022
8EA1	Structure of kudzu 2-hydroxyisoflavanone dehydratase in complex with P-NITROPHENOL 分子名称: 2-hydroxyisoflavanone dehydratase, P-NITROPHENOL 著者 Pan, H, Wang, X. 登録日 2022-08-27 公開日 2022-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 The protein conformational basis of isoflavone biosynthesis. Commun Biol, 5, 2022
7MSL	Structure of anti-CRISPR AcrIIC4 from Haemophilus parainfluenzae 分子名称: AcrIIC4, IODIDE ION 著者 Pan, C, Maxwell, K.L, Moraes, T.F. 登録日 2021-05-11 公開日 2022-03-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4 Hpa. J.Mol.Biol., 434, 2022
6IJJ	Photosystem I of Chlamydomonas reinhardtii 分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... 著者 Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. 登録日 2018-10-10 公開日 2019-03-20 最終更新日 2019-05-01 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex. Nat Plants, 5, 2019
6IJO	Photosystem I of Chlamydomonas reinhardtii 分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... 著者 Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. 登録日 2018-10-10 公開日 2019-03-20 最終更新日 2019-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex. Nat Plants, 5, 2019
7K3X	SGMGCIT segment 58-64 from Keratin-8 with G62C mutation 分子名称: ISOPROPYL ALCOHOL, SGMGCIT segment 58-64 from Keratin-8 with G62C mutation 著者 Murray, K.A, Sawaya, M.R, Eisenberg, D.S. 登録日 2020-09-14 公開日 2021-11-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
8BSE	CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD) in complex with 1D1 Fab 分子名称: 1D1 FAB HEAVY CHAIN, 1D1 FAB LIGHT CHAIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Welin, M, Kimbung, Y.R, Focht, D, Pisitkun, T. 登録日 2022-11-25 公開日 2023-05-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Efficacy of the combination of monoclonal antibodies against the SARS-CoV-2 Beta and Delta variants. Plos One, 18, 2023
7RD1	The Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25 分子名称: Hexon protein, Hexon-interlacing protein, Penton protein, ... 著者 Baker, A.T, Boyd, R.J, Sarkar, D, Vermaas, J.V, Williams, D, Singharoy, A. 登録日 2021-07-08 公開日 2021-12-15 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Sci Adv, 7, 2021
3CYY	The crystal structure of ZO-1 PDZ2 in complex with the Cx43 peptide 分子名称: Tight junction protein ZO-1, peptide from Gap junction alpha-1 protein 著者 Pan, L, Zhang, M. 登録日 2008-04-27 公開日 2008-09-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites Embo J., 27, 2008
4XML	Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424 分子名称: Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424 著者 Pan, R, Kong, X.-P. 登録日 2015-01-14 公開日 2015-07-08 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL. J.Virol., 89, 2015
3CQW	Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor 分子名称: 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, Glycogen synthase kinase-3 beta, MANGANESE (II) ION, ... 著者 Pandit, J. 登録日 2008-04-03 公開日 2008-05-27 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis and structure based optimization of novel Akt inhibitors Bioorg.Med.Chem.Lett., 18, 2008
6RGK	Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-055 分子名称: 3-[5-[(4~{a}~{R},8~{a}~{S})-3-cycloheptyl-4-oxidanylidene-4~{a},5,6,7,8,8~{a}-hexahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-butyl-prop-2-ynamide, FORMIC ACID, GLYCEROL, ... 著者 Singh, A.K, Brown, D.G. 登録日 2019-04-16 公開日 2019-07-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorg.Med.Chem., 27, 2019
8AXJ	Crystal structure of the N-terminal domain of Trypanosoma brucei CFAP410 分子名称: Chains: A, GLYCEROL, PHOSPHATE ION 著者 Dong, G, Stadler, A. 登録日 2022-08-31 公開日 2023-09-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Structural studies of cilia and flagella associated protein 410 (CFAP410) reveal its bimodular organization with an N-terminal LRR motif and a C-terminal tetrameric helical bundle To Be Published
8BK4	Full length structure of the apo-state LpMIP. 分子名称: (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-[(1~{S})-1-pyridin-2-ylethyl]-3,10-diazabicyclo[4.3.1]decan-2-one, GLYCEROL, Macrophage infectivity potentiator, ... 著者 Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A. 登録日 2022-11-08 公開日 2023-09-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding. Int.J.Biol.Macromol., 252, 2023
7WNI	Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor Y13158 分子名称: 1,2-ETHANEDIOL, 7-[2-[2,4-bis(fluoranyl)phenoxy]-5-(2-oxidanylpropan-2-yl)phenyl]-2-[4-(2-hydroxyethyloxy)-3,5-dimethyl-phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, DI(HYDROXYETHYL)ETHER, ... 著者 Li, J, Zhang, C, Xu, H, Zhuang, X, Wu, X, Zhang, Y, Xu, Y. 登録日 2022-01-18 公開日 2022-08-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Structure-Based Discovery and Optimization of Furo[3,2- c ]pyridin-4(5 H )-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors. J.Med.Chem., 65, 2022
7WFF	Subcomplexes B,M and L in the Cylic electron transfer supercomplex NDH-PSI from Arabidopsis 分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Pan, X.W, Li, M. 登録日 2021-12-26 公開日 2022-03-16 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 Supramolecular assembly of chloroplast NADH dehydrogenase-like complex with photosystem I from Arabidopsis thaliana. Mol Plant, 15, 2022

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