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2PA2
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Crystal structure of human Ribosomal protein L10 core domain
分子名称: 60S ribosomal protein L10, POTASSIUM ION
著者Nishimura, M, Kaminishi, T, Takemoto, C, Kawazoe, M, Yoshida, T, Tanaka, A, Sugano, S, Shirouzu, M, Ohkubo, T, Yokoyama, S, Kobayashi, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-27
公開日2008-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Ribosomal Protein L10 Core Domain Reveals Eukaryote-Specific Motifs in Addition to the Conserved Fold
J.Mol.Biol., 377, 2008
6BVF
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Cryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the fluorescent allosteric modulator HAP-TAMRA
分子名称: Capsid protein, Heteroaryldihydropyrimidine tetramethylrodamine
著者Schlicksup, C, Wang, J.C, Zlotnick, A.
登録日2017-12-12
公開日2018-02-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids.
Elife, 7, 2018
6BXZ
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Crystal Structure of Pig Protocadherin-15 EC10-MAD12
分子名称: CALCIUM ION, Protocadherin related 15
著者De-la-Torre, P, Araya-Secchi, R, Choudhary, D, Sotomayor, M.
登録日2017-12-19
公開日2018-11-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15.
Biophys. J., 115, 2018
6MLR
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BU of 6mlr by Molmil
Cryo-EM structure of microtubule-bound Kif7 in the AMPPNP state
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF7, ...
著者Mani, N, Jiang, S, Wilson-Kubalek, E.M, Ku, P, Milligan, R.A, Subramanian, R.
登録日2018-09-27
公開日2019-05-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7.
Dev.Cell, 49, 2019
1Q0Q
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BU of 1q0q by Molmil
Crystal structure of DXR in complex with the substrate 1-deoxy-D-xylulose-5-phosphate
分子名称: 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Mac Sweeney, A, Lange, R, D'Arcy, A, Douangamath, A, Surivet, J.-P, Oefner, C.
登録日2003-07-17
公開日2004-07-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
J.Mol.Biol., 345, 2005
1F0Z
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SOLUTION STRUCTURE OF THIS, THE SULFUR CARRIER PROTEIN IN E.COLI THIAMIN BIOSYNTHESIS
分子名称: THIS PROTEIN
著者Wang, C, Xi, J, Begley, T.P, Nicholson, L.K.
登録日2000-05-17
公開日2001-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of ThiS and implications for the evolutionary roots of ubiquitin.
Nat.Struct.Biol., 8, 2001
1ZLY
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BU of 1zly by Molmil
The structure of human glycinamide ribonucleotide transformylase in complex with alpha,beta-N-(hydroxyacetyl)-D-ribofuranosylamine and 10-formyl-5,8,dideazafolate
分子名称: 4-[(4-{[(2-AMINO-4-OXO-3,4-DIHYDROQUINAZOLIN-6-YL)METHYL]AMINO}BENZOYL)AMINO]BUTANOIC ACID, 5-O-phosphono-beta-D-ribofuranosylamine, Phosphoribosylglycinamide formyltransferase
著者Dahms, T.E.S, Sainz, G, Giroux, E.L, Caperelli, C.A, Smith, J.L.
登録日2005-05-09
公開日2005-08-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase.
Biochemistry, 44, 2005
1Q0L
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Crystal structure of DXR in complex with fosmidomycin
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Mac Sweeney, A, Lange, R, D'Arcy, A, Douangamath, A, Surivet, J.-P, Oefner, C.
登録日2003-07-16
公開日2004-07-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
J.Mol.Biol., 345, 2005
1Q0H
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BU of 1q0h by Molmil
Crystal structure of selenomethionine-labelled DXR in complex with fosmidomycin
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, CITRIC ACID, ...
著者Mac Sweeney, A, Lange, R, D'Arcy, A, Douangamath, A, Surivet, J.-P, Oefner, C.
登録日2003-07-16
公開日2004-07-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
J.Mol.Biol., 345, 2005
1G09
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CARBONMONOXY LIGANDED BOVINE HEMOGLOBIN PH 7.2
分子名称: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
著者Mueser, T.C, Rogers, P.H, Arnone, A.
登録日2000-10-05
公開日2000-12-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
1ZLX
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BU of 1zlx by Molmil
The apo structure of human glycinamide ribonucleotide transformylase
分子名称: GLYCEROL, Phosphoribosylglycinamide formyltransferase
著者Dahms, T.E, Sainz, G, Giroux, E.L, Caperelli, C.A, Smith, J.L.
登録日2005-05-09
公開日2005-08-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase.
Biochemistry, 44, 2005
1G0A
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CARBONMONOXY LIGANDED BOVINE HEMOGLOBIN PH 8.5
分子名称: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
著者Mueser, T.C, Rogers, P.H, Arnone, A.
登録日2000-10-05
公開日2000-12-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
1G9M
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
著者Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A.
登録日2000-11-24
公開日2000-12-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1UY4
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BU of 1uy4 by Molmil
Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
分子名称: CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, GLYCEROL, ...
著者Van Bueren, A.L, Boraston, A.B.
登録日2004-03-01
公開日2004-06-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Binding Sub-Site Dissection of a Carbohydrate-Binding Module Reveals the Contribution of Entropy to Oligosaccharide Recognition at "Non-Primary" Binding Subsites.
J.Mol.Biol., 340, 2004
2Q17
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BU of 2q17 by Molmil
Formylglycine Generating Enzyme from Streptomyces coelicolor
分子名称: CALCIUM ION, formylglycine generating enzyme
著者Carlson, B.L, Ballister, E.R, Skordalakes, E, King, D.S, Breidenbach, M.A, Gilmore, S.A, Berger, J.M, Bertozzi, C.R.
登録日2007-05-23
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Function and structure of a prokaryotic formylglycine-generating enzyme.
J.Biol.Chem., 283, 2008
1G9N
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BU of 1g9n by Molmil
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
著者Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A.
登録日2000-11-25
公開日2000-12-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1G08
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BU of 1g08 by Molmil
CARBONMONOXY LIGANDED BOVINE HEMOGLOBIN PH 5.0
分子名称: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
著者Mueser, T.C, Rogers, P.H, Arnone, A.
登録日2000-10-05
公開日2000-12-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
2Q40
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Ensemble refinement of the protein crystal structure of gene product from Arabidopsis thaliana At2g17340
分子名称: MAGNESIUM ION, Protein At2g17340
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-31
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
4I88
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R107G HSP16.5
分子名称: Small heat shock protein HSP16.5
著者Pohl, E, Williamson, I.R, Quinlan, R.A.
登録日2012-12-03
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Changes in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the alpha-crystallin domain.
PHILOS.TRANS.R.SOC.LOND.B BIOL.SCI., 368, 2013
4I5Z
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BU of 4i5z by Molmil
Insulin protein crystallization via langmuir-blodgett
分子名称: Insulin
著者Belmonte, L, Pechkova, E, Bragazzi, N, Nicolini, C.
登録日2012-11-29
公開日2013-11-20
最終更新日2015-12-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A review of the strategies for obtaining high-quality crystals utilizing nanotechnologies and microgravity
Crit Rev Eukaryot Gene Expr, 24, 2014
3KDY
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BU of 3kdy by Molmil
X-ray crystal structure of tyrosine aminomutase mutant construct
分子名称: Histidine ammonia-lyase
著者Cooke, H.A, Bruner, S.D.
登録日2009-10-23
公開日2010-07-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Probing the active site of MIO-dependent aminomutases, key catalysts in the biosynthesis of beta-amino acids incorporated in secondary metabolites
Biopolymers, 93, 2010
5UFR
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Structure of RORgt bound to
分子名称: (S)-[4-chloro-2-(dimethylamino)-3-phenylquinolin-6-yl](1-methyl-1H-imidazol-5-yl)(pyridin-4-yl)methanol, Nuclear receptor ROR-gamma
著者Spurlino, J, Abad, M.
登録日2017-01-05
公開日2017-04-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.068 Å)
主引用文献Identification and structure activity relationships of quinoline tertiary alcohol modulators of ROR gamma t.
Bioorg. Med. Chem. Lett., 27, 2017
6PD9
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BU of 6pd9 by Molmil
Crystal structure of MYST acetyltransferase domain in complex with inhibitor 60
分子名称: 2-fluoro-3-methyl-N'-(phenylsulfonyl)-5-(1H-pyrazol-1-yl)benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ...
著者Hermans, S.J, Parker, M.W, Thomas, T, Baell, J.B.
登録日2019-06-18
公開日2020-04-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J.Med.Chem., 63, 2020
6PDF
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BU of 6pdf by Molmil
Crystal structure of MYST acetyltransferase domain in complex with inhibitor 55
分子名称: 2-fluoro-3-methyl-N'-(phenylsulfonyl)-5-(2H-1,2,3-triazol-2-yl)benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ...
著者Hermans, S.J, Parker, M.W, Thomas, T, Baell, J.B.
登録日2019-06-18
公開日2020-04-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J.Med.Chem., 63, 2020
6PD8
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Crystal structure of MYST acetyltransferase domain in complex with inhibitor 39
分子名称: 5-ethoxy-2-fluoro-3-methyl-N'-(phenylsulfonyl)benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ...
著者Hermans, S.J, Parker, M.W, Thomas, T, Baell, J.B.
登録日2019-06-18
公開日2020-04-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.738 Å)
主引用文献Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J.Med.Chem., 63, 2020

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