1ZLX

The apo structure of human glycinamide ribonucleotide transformylase

Summary for 1ZLX

Entry DOI	10.2210/pdb1zlx/pdb
Related	1MEJ 1MEN 1MEO 1NJS
Descriptor	Phosphoribosylglycinamide formyltransferase, GLYCEROL (3 entities in total)
Functional Keywords	seven stranded beta-pleated sheet, modified doubly wound alpha/beta sheet, mononucleotide binding domain (beta-alpha-beta-alpha-beta), phosphate binding loop, folate binding loop, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	22035.95
Authors	Dahms, T.E.,Sainz, G.,Giroux, E.L.,Caperelli, C.A.,Smith, J.L. (deposition date: 2005-05-09, release date: 2005-08-23, Last modification date: 2023-11-15)
Primary citation	Dahms, T.E.,Sainz, G.,Giroux, E.L.,Caperelli, C.A.,Smith, J.L. The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase. Biochemistry, 44:9841-9850, 2005 Cited by PubMed: 16026156 DOI: 10.1021/bi050307g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation