1Q0H

Crystal structure of selenomethionine-labelled DXR in complex with fosmidomycin

Summary for 1Q0H

Entry DOI	10.2210/pdb1q0h/pdb
Related	1Q0L 1Q0Q
Descriptor	1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	46416.52
Authors	Mac Sweeney, A.,Lange, R.,D'Arcy, A.,Douangamath, A.,Surivet, J.-P.,Oefner, C. (deposition date: 2003-07-16, release date: 2004-07-20, Last modification date: 2023-11-15)
Primary citation	Mac Sweeney, A.,Lange, R.,Fernandes, R.P.,Schulz, H.,Dale, G.E.,Douangamath, A.,Proteau, P.J.,Oefner, C. The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation. J.Mol.Biol., 345:115-127, 2005 Cited by PubMed: 15567415 DOI: 10.1016/j.jmb.2004.10.030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation