PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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4R7E	Structure of Bre1 RING domain 分子名称: E3 ubiquitin-protein ligase BRE1, ZINC ION 著者 Kumar, P, Wolberger, C. 登録日 2014-08-27 公開日 2015-05-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.251 Å) 主引用文献 Structure of the yeast Bre1 RING domain. Proteins, 83, 2015
7KX4	Anti-CCHFV ADI-36121 Fab 分子名称: ADI-36121 Fab heavy chain, ADI-36121 Fab light chain 著者 Mishra, A.K, McLellan, J.S. 登録日 2020-12-03 公開日 2021-12-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
4R90	Anti CD70 Llama glama Fab 27B3 分子名称: Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ... 著者 Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. 登録日 2014-09-03 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
4R0U	Tgvtava, an amyloid forming segment from alpha synuclein, residues 72-78 分子名称: Alpha-synuclein 著者 Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R. 登録日 2014-08-01 公開日 2014-12-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014
4R4S	Crystal structure of chimeric beta-lactamase cTEM-19m at 1.1 angstrom resolution 分子名称: Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION 著者 Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. 登録日 2014-08-19 公開日 2015-11-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Sci Rep, 9, 2019
3FB3	Crystal Structure of Trypanosoma Brucei Acetyltransferase, Tb11.01.2886 分子名称: N-acetyltransferase 著者 Wernimont, A.K, Marino, K, Zhang, A.Z, Ma, D, Lin, Y.H, MacKenzie, F, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Ferguson, M.A.J, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) 登録日 2008-11-18 公開日 2008-11-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structure of Trypanosoma Brucei Acetyltransferase, Tb11.01.2886 TO BE PUBLISHED
4R96	Structure of a Llama Glama Fab 48A2 against human cMet 分子名称: Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain 著者 Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. 登録日 2014-09-03 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
7KGB	CryoEM structure of A2296-methylated Mycobacterium tuberculosis ribosome bound with SEQ-9 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Cui, Z, Zhang, J. 登録日 2020-10-16 公開日 2022-01-19 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 2023
4R0P	Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61 分子名称: Lysozyme C 著者 Sievers, S, Eisenberg, D.S, Sawaya, M.R. 登録日 2014-08-01 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014
3G4D	Crystal Structure of (+)-delta-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for Catalysis 分子名称: (+)-delta-cadinene synthase isozyme XC1, BETA-MERCAPTOETHANOL, GLYCEROL 著者 Gennadios, H.A, Di Costanzo, L, Miller, D.J, Allemann, R.K, Christianson, D.W. 登録日 2009-02-03 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
3DKH	L559A mutant of Melanocarpus albomyces laccase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Hakulinen, N, Rouvinen, J. 登録日 2008-06-25 公開日 2009-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure Febs J., 276, 2009
4QXU	Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody 分子名称: Matrix metalloproteinase-14, SULFATE ION, anti_MT1-MMP Heavy chain, ... 著者 Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Moreno, v, Cuiniasse, P, Dive, V, Arroyo, A.G, Sagi, I, Israel Structural Proteomics Center (ISPC) 登録日 2014-07-22 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
6WJ0	Crystal structure of Fab 54-4H03 分子名称: Fab 54-4H03 heavy chain, Fab 54-4H03 light chain, GLYCEROL 著者 Wu, N.C, Wilson, I.A. 登録日 2020-04-11 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
4QXS	Crystal structure of human FPPS in complex with WC01088 分子名称: (2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Park, J, Zielinski, M, Weiling, C, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2014-07-21 公開日 2015-02-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorg.Med.Chem.Lett., 25, 2015
4QY5	Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations 分子名称: Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION 著者 Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. 登録日 2014-07-23 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations To be Published
4QXW	Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain 分子名称: Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside 著者 Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. 登録日 2014-07-22 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
4RG3	Epsilon-caprolactone-bound crystal structure of cyclohexanone monooxygenase in the Tight conformation 分子名称: BICINE, Caprolactone, Cyclohexanone monooxygenase, ... 著者 Yachnin, B.J, Berghuis, A.M. 登録日 2014-09-29 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Lactone-bound structures of cyclohexanone monooxygenase provide insight into the stereochemistry of catalysis. Acs Chem.Biol., 9, 2014
5FH0	The structure of rat cytosolic PEPCK variant E89A complex with GTP 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2015-12-21 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH4	The structure of rat cytosolic PEPCK variant E89D in complex with beta-sulfopyruvate and GTP 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2015-12-21 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
4R0W	Vvtgvta, an amyloid forming segment from alpha synuclein, residues 70-76 分子名称: Alpha-synuclein 著者 Ivanova, M.I, Eisenberg, D.S, Sawaya, M.R. 登録日 2014-08-01 公開日 2014-12-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014
6WJ1	Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-4H03 heavy chain, ... 著者 Wu, N.C, Wilson, I.A. 登録日 2020-04-11 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.503 Å) 主引用文献 Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
4RIK	Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 分子名称: Alpha-synuclein 著者 Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. 登録日 2014-10-06 公開日 2015-08-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.854 Å) 主引用文献 Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
4RIL	Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction 分子名称: Alpha-synuclein 著者 Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. 登録日 2014-10-06 公開日 2015-08-26 最終更新日 2023-09-20 実験手法 ELECTRON CRYSTALLOGRAPHY (1.43 Å) 主引用文献 Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
6WIY	Crystal structure of Fab 54-1G05 分子名称: Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, GLYCEROL 著者 Wu, N.C, Wilson, I.A. 登録日 2020-04-11 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
4TLU	Crystal Structure of Human Transthyretin Ala108Trp Mutant 分子名称: CHLORIDE ION, Transthyretin 著者 Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. 登録日 2014-05-30 公開日 2015-12-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of Human Transthyretin Ala108Trp Mutant to be published

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