4R90

Anti CD70 Llama glama Fab 27B3

Summary for 4R90

DescriptorAnti CD70 Llama glama Fab 27B3 Light chain, Anti CD70 Llama glama Fab 27B3 Heavy chain, GLYCEROL, ... (5 entities in total)
Functional Keywordsimmunoglobulin fold, immune system, human cd70
Biological sourceLlama glama
More
Total number of polymer chains2
Total molecular weight47380.71
Authors
Klarenbeek, A.,El Mazouari, K.,Desmyter, A.,Blanchetot, C.,Hultberg, A.,Roovers, R.C.,Cambillau, C.,Spinelli, S.,Del-Favero, J.,Verrips, T.,de Haard, H.,Achour, I. (deposition date: 2014-09-03, release date: 2015-06-24, Last modification date: 2017-11-22)
Primary citation
Klarenbeek, A.,Mazouari, K.E.,Desmyter, A.,Blanchetot, C.,Hultberg, A.,de Jonge, N.,Roovers, R.C.,Cambillau, C.,Spinelli, S.,Del-Favero, J.,Verrips, T.,de Haard, H.J.,Achour, I.
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
MAbs, 7:693-706, 2015
PubMed: 26018625 (PDB entries with the same primary citation)
DOI: 10.1080/19420862.2015.1046648
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.746 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.191401.6%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12