4R96
Structure of a Llama Glama Fab 48A2 against human cMet
Summary for 4R96
Entry DOI | 10.2210/pdb4r96/pdb |
Descriptor | Llama glama Fab 48A2 against human cMet L chain, Llama glama Fab 48A2 against human cMet H chain (3 entities in total) |
Functional Keywords | immunoglobulin domains, immune system, cmet |
Biological source | Llama Glama More |
Total number of polymer chains | 8 |
Total formula weight | 191532.41 |
Authors | Klarenbeek, A.,El Mazouari, K.,Desmyter, A.,Blanchetot, C.,Hultberg, A.,Roovers, R.C.,Cambillau, C.,Spinelli, S.,Del-Favero, J.,Verrips, T.,de Haard, H.,Achour, I. (deposition date: 2014-09-03, release date: 2015-06-24, Last modification date: 2023-09-20) |
Primary citation | Klarenbeek, A.,Mazouari, K.E.,Desmyter, A.,Blanchetot, C.,Hultberg, A.,de Jonge, N.,Roovers, R.C.,Cambillau, C.,Spinelli, S.,Del-Favero, J.,Verrips, T.,de Haard, H.J.,Achour, I. Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7:693-706, 2015 Cited by PubMed: 26018625DOI: 10.1080/19420862.2015.1046648 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.31 Å) |
Structure validation
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