4R96

Structure of a Llama Glama Fab 48A2 against human cMet

Summary for 4R96

• Entry DOI: 10.2210/pdb4r96/pdb
• Descriptor: Llama glama Fab 48A2 against human cMet L chain, Llama glama Fab 48A2 against human cMet H chain (3 entities in total)
• Functional Keywords: immunoglobulin domains, immune system, cmet
• Biological source: Llama Glama; More
• Total number of polymer chains: 8
• Total formula weight: 191532.41

Authors

Klarenbeek, A.,El Mazouari, K.,Desmyter, A.,Blanchetot, C.,Hultberg, A.,Roovers, R.C.,Cambillau, C.,Spinelli, S.,Del-Favero, J.,Verrips, T.,de Haard, H.,Achour, I. (deposition date: 2014-09-03, release date: 2015-06-24, Last modification date: 2023-09-20)

• Primary citation: Klarenbeek, A.,Mazouari, K.E.,Desmyter, A.,Blanchetot, C.,Hultberg, A.,de Jonge, N.,Roovers, R.C.,Cambillau, C.,Spinelli, S.,Del-Favero, J.,Verrips, T.,de Haard, H.J.,Achour, I.; Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.; MAbs, 7:693-706, 2015; PubMed: 26018625; DOI: 10.1080/19420862.2015.1046648

Experimental method

X-RAY DIFFRACTION (3.31 Å)