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PDB: 1 results

4QXS
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BU of 4qxs by Molmil
Crystal structure of human FPPS in complex with WC01088
Descriptor: (2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, GLYCEROL, ...
Authors:Park, J, Zielinski, M, Weiling, C, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2014-07-21
Release date:2015-02-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase.
Bioorg.Med.Chem.Lett., 25, 2015

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