PDB: 10530 件ウェブページステータス検索Chemie searchBIRD

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5WUE	Structural basis for conductance through TRIC cation channels 分子名称: SULFATE ION, Uncharacterized protein 著者 Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2016-12-17 公開日 2017-06-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for conductance through TRIC cation channels. Nat Commun, 8, 2017
5YKG	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.57 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5Y2G	Structure of MBP tagged GBS CAMP 分子名称: Maltose-binding periplasmic protein,Protein B, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Jin, T, Li, Y. 登録日 2017-07-25 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure determination of the CAMP factor of Streptococcus agalactiae with the aid of an MBP tag and insights into membrane-surface attachment. Acta Crystallogr D Struct Biol, 75, 2019
5Y5V	Crystal structure of a novel Pyrethroid Hydrolase PytH (S78A) 分子名称: Pyrethroid hydrolase, SULFATE ION 著者 Xu, D.Q, Ran, T.T, He, J, Wang, W.W. 登録日 2017-08-09 公開日 2018-08-15 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Structure and Catalytic Mechanism of a Novel Pyrethroid Hydrolase from Sphingobium faniae JZ-2 To Be Published
5YAC	Crystal structure of WT Trm5b from Pyrococcus abyssi 分子名称: tRNA (guanine(37)-N1)-methyltransferase Trm5b 著者 Xie, W, Wu, J. 登録日 2017-08-31 公開日 2017-09-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 The crystal structure of the Pyrococcus abyssi mono-functional methyltransferase PaTrm5b Biochem. Biophys. Res. Commun., 493, 2017
5YE5	structure of endo-lysosomal TRPML1 channel inserting into nanodisc 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, mammalian endo-lysosomal TRPML1 channel 著者 Yang, M, Gao, N. 登録日 2017-09-15 公開日 2017-11-15 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017
5YDZ	structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 1 分子名称: mammalian endo-lysosomal TRPML1 channel 著者 Yang, M, Gao, N. 登録日 2017-09-15 公開日 2017-12-27 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017
5YKE	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.11 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5WUK	Crystal structure of EED [G255D] in complex with EZH2 peptide and EED226 compound 分子名称: GLYCEROL, Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... 著者 Chen, Z. 登録日 2016-12-19 公開日 2017-05-03 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Split luciferase-based biosensors for characterizing EED binders Anal. Biochem., 522, 2017
5WO4	JAK1 complexed with compound 28 分子名称: 3-[(4-chloro-3-methoxyphenyl)amino]-1-[(3R,4S)-4-cyanooxan-3-yl]-1H-pyrazole-4-carboxamide, Tyrosine-protein kinase JAK1 著者 Lesburg, C.A, Patel, S.B. 登録日 2017-08-01 公開日 2017-12-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The Discovery of 3-((4-Chloro-3-methoxyphenyl)amino)-1-((3R,4S)-4-cyanotetrahydro-2H-pyran-3-yl)-1H-pyrazole-4-carboxamide, a Highly Ligand Efficient and Efficacious Janus Kinase 1 Selective Inhibitor with Favorable Pharmacokinetic Properties. J. Med. Chem., 60, 2017
5WPT	Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION 著者 Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. 登録日 2017-08-07 公開日 2017-10-18 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017
5YGS	Human TNFRSF25 death domain 分子名称: Human TNRSF25 death domain, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Yin, X, Jin, T. 登録日 2017-09-26 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.691 Å) 主引用文献 Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
5YI7	Crystal structure of drosophila Numb PTB domain and Pon peptide complex 分子名称: GLYCEROL, Pon peptide from Partner of numb, Protein numb 著者 Shan, Z, Wen, W. 登録日 2017-10-03 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nat Commun, 9, 2018
5WT3	Pyrococcus abyssi methyltransferase PaTrm5a bound by MTA and cognate tRNA 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, RNA (73-MER), tRNA (guanine(37)-N1)-methyltransferase Trm5a 著者 Xie, W, Wang, C, Jia, Q. 登録日 2016-12-09 公開日 2017-12-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.204 Å) 主引用文献 Structural insight into the methyltransfer mechanism of the bifunctional Trm5. Sci Adv, 3, 2017
5YWC	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW9	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWB	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-30 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5ZFM	Ketoreductase LbCR mutant - M6 分子名称: 3-oxoacyl-acyl carrier protein reductase 著者 Gong, X.M, Zheng, G.W, Xu, J.H. 登録日 2018-03-06 公開日 2019-01-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor Acs Catalysis, 9, 2019
5YW8	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5ZGU	Crystal structure of NDM-1 at pH7.0 (HEPES) with 2 molecules per asymmetric unit 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HYDROXIDE ION, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZI0	Ketoreductase LbCR mutant - M8 分子名称: 3-oxoacyl-acyl carrier protein reductase 著者 Gong, X.M, Zheng, G.W, Xu, J.H. 登録日 2018-03-14 公開日 2019-01-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor Acs Catalysis, 9, 2019
5Z96	Structure of the mouse TRPC4 ion channel 分子名称: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... 著者 Duan, J, Li, Z, Li, J, Zhang, J. 登録日 2018-02-02 公開日 2018-04-18 最終更新日 2018-08-29 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Structure of the mouse TRPC4 ion channel. Nat Commun, 9, 2018
5WPV	Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs at 3.59 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION 著者 Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. 登録日 2017-08-07 公開日 2017-10-18 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017
5WUC	Structural basis for conductance through TRIC cation channels 分子名称: SODIUM ION, Uncharacterized protein 著者 Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2016-12-17 公開日 2017-07-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for conductance through TRIC cation channels. Nat Commun, 8, 2017
5YWD	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018

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