5ZI0

Ketoreductase LbCR mutant - M8

Summary for 5ZI0

Entry DOI	10.2210/pdb5zi0/pdb
Descriptor	3-oxoacyl-acyl carrier protein reductase (2 entities in total)
Functional Keywords	ketoreductase, short-chain dehydrogenase/reductase (sdr), oxidoreductase
Biological source	Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Total number of polymer chains	4
Total formula weight	118269.93
Authors	Gong, X.M.,Zheng, G.W.,Xu, J.H. (deposition date: 2018-03-14, release date: 2019-01-16, Last modification date: 2024-03-27)
Primary citation	Gong, X.M.,Zhen, Q.,Li, F.L.,Zeng, B.B.,Zheng, G.W.,Xu, J.H. Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor Acs Catalysis, 9:147-153, 2019 Cited by DOI: 10.1021/acscatal.8b03382 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.302 Å)

Structure validation