5YW8
 
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7U32
 | | MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution | | 分子名称: | CALCIUM ION, DNA EV272, DNA EV273, ... | | 著者 | Shan, Z, Pye, V.E, Cherepanov, P, Lyumkis, D. | | 登録日 | 2022-02-25 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Multivalent interactions essential for lentiviral integrase function.
Nat Commun, 13, 2022
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5YWD
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5K0C
 | | Crystal Structure of COMT in complex with 2,4-dimethyl-5-[3-(2-phenylpropan-2-yl)-1H-pyrazol-5-yl]-1,3-thiazole | | 分子名称: | 1,2-ETHANEDIOL, 2,4-dimethyl-5-[3-(2-phenylpropan-2-yl)-1H-pyrazol-5-yl]-1,3-thiazole, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... | | 著者 | Ehler, A, Rodriguez-Sarmiento, R.M, Rudolph, M.G. | | 登録日 | 2016-05-17 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket.
J. Med. Chem., 59, 2016
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6TKO
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7TYT
 | | Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Shyng, S.L, Sung, M.W, Driggers, C.M. | | 登録日 | 2022-02-14 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
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7U1S
 | | Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Shyng, S.L, Sung, M.W, Driggers, C.M. | | 登録日 | 2022-02-22 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
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7U1Q
 | | Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Shyng, S.L, Sung, M.W, Driggers, C.M. | | 登録日 | 2022-02-21 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
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7U6Y
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5YW7
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5YWA
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2GMX
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7UX7
 | | Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH bound at 1.2 A resolution (P212121 - form II) | | 分子名称: | MfnG, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN LIGAND | | 著者 | Miller, M.D, Wu, K.-L, Xu, W, Xiao, H, Philips Jr, G.N. | | 登録日 | 2022-05-05 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid.
Protein Sci., 31, 2022
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6IBL
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80 | | 分子名称: | Camelid antibody fragment Nb80, HEGA-10, SODIUM ION, ... | | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor.
Nature, 583, 2020
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2AFE
 | | Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence | | 分子名称: | protein Asl1650 | | 著者 | Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | 登録日 | 2005-07-25 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
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1IS0
 | | Crystal Structure of a Complex of the Src SH2 Domain with Conformationally Constrained Peptide Inhibitor | | 分子名称: | AY0 GLU GLU ILE peptide, Tyrosine-protein kinase transforming protein SRC | | 著者 | Davidson, J.P, Lubman, O, Rose, T, Waksman, G, Martin, S.F. | | 登録日 | 2001-11-02 | | 公開日 | 2002-02-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding.
J.Am.Chem.Soc., 124, 2002
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2AFD
 | | Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence | | 分子名称: | protein Asl1650 | | 著者 | Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | 登録日 | 2005-07-25 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
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6R9W
 | | Crystal structure of InhA in complex with AP-124 inhibitor | | 分子名称: | (2~{S})-1-(benzimidazol-1-yl)-3-(2,3-dihydro-1~{H}-inden-5-yloxy)propan-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Takebayashi, Y, Hinchliffe, P, Spencer, J. | | 登録日 | 2019-04-04 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography.
J.Chem.Inf.Model., 60, 2020
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3J7W
 | | Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions | | 分子名称: | Major capsid protein 10A | | 著者 | Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W. | | 登録日 | 2014-08-12 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
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7AOI
 | | Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate | | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | | 著者 | Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A. | | 登録日 | 2020-10-14 | | 公開日 | 2020-12-02 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
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4MIC
 | | Crystal structure of Gpb in complex with SUGAR (N-{(2E)-3-[4-(PROPAN-2-YL)PHENYL]PROP-2-ENOYL}-BETA-D-GLUCOPYRANOSYLAMINE) (S6) | | 分子名称: | Glycogen phosphorylase, muscle form, N-{(2E)-3-[4-(propan-2-yl)phenyl]prop-2-enoyl}-beta-D-glucopyranosylamine | | 著者 | Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. | | 登録日 | 2013-08-30 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure based inhibitor design targeting glycogen phosphorylase b. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-beta-d-glucopyranosylamines.
Bioorg.Med.Chem., 22, 2014
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3RU5
 | | Silver Metallated Hen Egg White Lysozyme at 1.35 A | | 分子名称: | 1,2-ETHANEDIOL, Lysozyme C, NITRATE ION, ... | | 著者 | Leeper, T.C, Panzner, M.J, Bilinovich, S.M. | | 登録日 | 2011-05-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Silver metallation of hen egg white lysozyme: X-ray crystal structure and NMR studies.
Chem.Commun.(Camb.), 47, 2011
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6JB1
 | | Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... | | 著者 | Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-22 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
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3J7X
 | | Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions | | 分子名称: | Major capsid protein 10A | | 著者 | Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W. | | 登録日 | 2014-08-12 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6SP2
 | | CryoEM structure of SERINC from Drosophila melanogaster | | 分子名称: | CARDIOLIPIN, Lauryl Maltose Neopentyl Glycol, Membrane protein TMS1d, ... | | 著者 | Pye, V.E, Nans, A, Cherepanov, P. | | 登録日 | 2019-08-30 | | 公開日 | 2020-01-01 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | A bipartite structural organization defines the SERINC family of HIV-1 restriction factors.
Nat.Struct.Mol.Biol., 27, 2020
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