6IBL

ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80

Replaces:  6H7K

Summary for 6IBL

• Entry DOI: 10.2210/pdb6ibl/pdb
• Descriptor: Thioredoxin 1,Beta-1 adrenergic receptor, Camelid antibody fragment Nb80, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide, ... (6 entities in total)
• Functional Keywords: beta1 adrenoceptor, activated, agonist, nanobody, immune system
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 4
• Total formula weight: 123393.64

Authors

Warne, T.,Edwards, P.C.,Dore, A.S.,Leslie, A.G.W.,Tate, C.G. (deposition date: 2018-11-30, release date: 2019-01-09, Last modification date: 2024-01-24)

• Primary citation: Lee, Y.,Warne, T.,Nehme, R.,Pandey, S.,Dwivedi-Agnihotri, H.,Chaturvedi, M.,Edwards, P.C.,Garcia-Nafria, J.,Leslie, A.G.W.,Shukla, A.K.,Tate, C.G.; Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor.; Nature, 583:862-866, 2020; PubMed: 32555462; DOI: 10.1038/s41586-020-2419-1

Experimental method

X-RAY DIFFRACTION (2.7 Å)