PDB: 2623 件ウェブページステータス検索Chemie searchBIRD

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7OYJ	Crystal structure of hTEAD2 in complex with fragment at the interface 2 分子名称: 3-(1~{H}-pyrazol-5-yl)aniline, PALMITIC ACID, Transcriptional enhancer factor TEF-4 著者 Guichou, J.F, Gelin, M, Allemand, F. 登録日 2021-06-24 公開日 2022-05-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs. J.Med.Chem., 65, 2022
5FOA	Crystal Structure of Human Complement C3b in complex with DAF (CCP2-4) 分子名称: COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA CHAIN, DECAY ACCELERATING FACTOR, ... 著者 Forneris, F, Wu, J, Xue, X, Gros, P. 登録日 2015-11-18 公開日 2016-04-06 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (4.188 Å) 主引用文献 Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode. Embo J., 35, 2016
5W59	Crystal structure of a monomeric human FGF9 in complex with the ectodomain of human FGFR1c 分子名称: Fibroblast growth factor 9, Fibroblast growth factor receptor 1, SULFATE ION 著者 Mohammadi, M, Ma, J, Liu, Y. 登録日 2017-06-14 公開日 2017-08-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization. Structure, 25, 2017
6WXU	CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state 分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIUNDECYL PHOSPHATIDYL CHOLINE, ... 著者 Sun, J. 登録日 2020-05-12 公開日 2020-09-02 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation. Nat.Struct.Mol.Biol., 27, 2020
6WXR	CryoEM structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, Dual oxidase maturation factor 1, ... 著者 Sun, J. 登録日 2020-05-11 公開日 2020-09-02 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation. Nat.Struct.Mol.Biol., 27, 2020
1OBP	ODORANT-BINDING PROTEIN FROM BOVINE NASAL MUCOSA 分子名称: ODORANT-BINDING PROTEIN, UNKNOWN ATOM OR ION 著者 Tegoni, M, Cambillau, C. 登録日 1996-01-14 公開日 1996-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Domain swapping creates a third putative combining site in bovine odorant binding protein dimer Nat.Struct.Biol., 3, 1996
4B1T	Structure of the factor Xa-like trypsin variant triple-Ala (TA) in complex with eglin C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Menzel, A, Neumann, P, Stubbs, M.T. 登録日 2012-07-12 公開日 2012-08-01 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
4B2B	Structure of the factor Xa-like trypsin variant triple-Ala (TGPA) in complex with eglin C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Menzel, A, Neumann, P, Stubbs, M.T. 登録日 2012-07-13 公開日 2012-08-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
4B2C	Structure of the factor Xa-like trypsin variant triple-Ala (TPA) in complex with eglin C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Menzel, A, Neumann, P, Stubbs, M.T. 登録日 2012-07-13 公開日 2012-08-01 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
4B2A	Structure of the factor Xa-like trypsin variant triple-Ala (TGA) in complex with eglin C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Menzel, A, Neumann, P, Stubbs, M.T. 登録日 2012-07-13 公開日 2012-08-01 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
4ZI3	BART-like domain of BARTL1/CCDC104 aa1-133 in complex with Arl3FL bound to GppNHp in P1 21 1 分子名称: ADP-ribosylation factor-like protein 3, Cilia- and flagella-associated protein 36, MAGNESIUM ION, ... 著者 Lokaj, M, Koerner, C, Koesling, S, Wittinghofer, A. 登録日 2015-04-27 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function. Structure, 23, 2015
3AB3	Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13 分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13, ... 著者 Kukimoto-Niino, M, Mishima, C, Shirouzu, M, Kozasa, T, Yokoyama, S. 登録日 2009-11-30 公開日 2010-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex. J.Biol.Chem., 286, 2011
5DMQ	Crystal structure of mouse eRF1 in complex with Reverse Transcriptase (RT) of Moloney Murine Leukemia Virus 分子名称: Eukaryotic peptide chain release factor subunit 1, Reverse transcriptase/ribonuclease H p80 著者 Tang, T, Song, H. 登録日 2015-09-09 公開日 2016-07-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus Nat Commun, 7, 2016
3NV0	Crystal structure and mutational analysis of the NXF2/NXT1 heterodimeric complex from caenorhabditis elegans at 1.84 A resolution 分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Kerkow, D.E, Carmel, A.B, Williamson, J.R. 登録日 2010-07-07 公開日 2011-07-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold. J.Mol.Biol., 415, 2012
1LE9	Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti 分子名称: 5'-D(*AP*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*T)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... 著者 Benjamin, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. 登録日 2002-04-09 公開日 2003-04-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. J.Biol.Chem., 277, 2002
1GMN	CRYSTAL STRUCTURES OF NK1-HEPARIN COMPLEXES REVEAL THE BASIS FOR NK1 ACTIVITY AND ENABLE ENGINEERING OF POTENT AGONISTS OF THE MET RECEPTOR 分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEPATOCYTE GROWTH FACTOR 著者 Lietha, D, Chirgadze, D.Y, Mulloy, B, Blundell, T.L, Gherardi, E. 登録日 2001-09-19 公開日 2001-10-02 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor Embo J., 20, 2001
3W3E	Structure of Vigna unguiculata chitinase with regulation activity of the plant cell wall 分子名称: Cotyledoneous yieldin-like protein 著者 Morohashi, K, Sasaki, K, Sakabe, N, Sakabe, K. 登録日 2012-12-20 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Three-dimensional structure analysis of Vigna unguiculata chitinase with regulation activity of the yield threshold of cell wall To be Published
4RE1	Crystal structure of human TEAD1 and disulfide-engineered YAP 分子名称: CHLORIDE ION, Transcriptional enhancer factor TEF-1, Yorkie homolog 著者 Xu, Z, Zhou, Z. 登録日 2014-09-21 公開日 2014-11-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides. Faseb J., 29, 2015
4WV1	Crystal structure of the FGFR2 D2 domain in complex with Fab 2B.1.3 分子名称: Fab heavy chain, Fab light chain, Fibroblast growth factor receptor 2 著者 Yin, Y, Carter, P.J. 登録日 2014-11-04 公開日 2015-09-16 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.362 Å) 主引用文献 Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity. Mol.Cancer Ther., 14, 2015
1JTZ	CRYSTAL STRUCTURE OF TRANCE/RANKL CYTOKINE. 分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 著者 Nelson, C.A, Fremont, D.H. 登録日 2001-08-23 公開日 2001-09-12 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity J.Clin.Invest., 108, 2001
5WI4	CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2 分子名称: Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION 著者 Balan, M, Ishiyama, N, Marshall, C.B, Ikura, M. 登録日 2017-07-18 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity. Sci Signal, 10, 2017
2F5J	Crystal structure of MRG domain from human MRG15 分子名称: Mortality factor 4-like protein 1 著者 Zhang, P, Du, J, Ding, J. 登録日 2005-11-26 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14 Protein Sci., 15, 2006
2QL2	Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA 分子名称: DNA (5'-D(*DAP*DGP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DTP*DGP*DGP*DCP*DCP*DTP*DA)-3'), DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), Neurogenic differentiation factor 1, ... 著者 Rose, R.B, Longo, A, Guanga, G.P. 登録日 2007-07-12 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry, 47, 2008
2C6Y	Crystal structure of interleukin enhancer-binding factor 1 bound to DNA 分子名称: FORKHEAD BOX PROTEIN K2, INTERLEUKIN 2 PROMOTOR, MAGNESIUM ION 著者 Tsai, K.-L, Huang, C.-Y, Chang, C.-H, Sun, Y.-J, Chuang, W.-J, Hsiao, C.-D. 登録日 2005-11-15 公開日 2006-04-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Human Foxk1A-DNA Complex and its Implications on the Diverse Binding Specificity of Winged Helix/Forkhead Proteins. J.Biol.Chem., 281, 2006
5GKB	Crystal Structure of Fatty Acid-Binding Protein in Brain Tissue of Drosophila melanogaster without citrate inside 分子名称: Fatty acid bindin protein, isoform B 著者 Cheng, Y.-Y, Huang, Y.-F, Lin, H.-H, Chang, W.W, Lyu, P.-C. 登録日 2016-07-04 公開日 2017-07-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 The ligand-mediated affinity of brain-type fatty acid-binding protein for membranes determines the directionality of lipophilic cargo transport. Biochim Biophys Acta Mol Cell Biol Lipids, 1864, 2019

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