5W59

Crystal structure of a monomeric human FGF9 in complex with the ectodomain of human FGFR1c

Summary for 5W59

• Entry DOI: 10.2210/pdb5w59/pdb
• Related: 1CVS 3OJV
• Descriptor: Fibroblast growth factor 9, Fibroblast growth factor receptor 1, SULFATE ION, ... (4 entities in total)
• Functional Keywords: growth factor, growth factor receptor, ligand-receptor complex, cytokine
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 45718.81

Authors

Mohammadi, M.,Ma, J.,Liu, Y. (deposition date: 2017-06-14, release date: 2017-08-16, Last modification date: 2023-10-04)

• Primary citation: Liu, Y.,Ma, J.,Beenken, A.,Srinivasan, L.,Eliseenkova, A.V.,Mohammadi, M.; Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization.; Structure, 25:1325-1336.e3, 2017; PubMed: 28757146; DOI: 10.1016/j.str.2017.06.016

Experimental method

X-RAY DIFFRACTION (2.498 Å)