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1A84
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NMR SOLUTION STRUCTURE OF A DNA DODECAMER DUPLEX CONTAINING A CIS-DIAMMINEPLATINUM(II) D(GPG) INTRASTRAND CROSS-LINK, THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN, 1 STRUCTURE
分子名称: Cisplatin, DNA D(CCTCTG*G*TCTCC), DNA D(GGAGACCAGAGG)
著者Gelasco, A, Lippard, S.J.
登録日1998-04-02
公開日1998-11-25
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin.
Biochemistry, 37, 1998
1A85
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MMP8 WITH MALONIC AND ASPARAGINE BASED INHIBITOR
分子名称: CALCIUM ION, MMP-8, N~1~-(3-aminobenzyl)-N~2~-[(2R)-2-(hydroxycarbamoyl)-4-methylpentanoyl]-L-aspartamide, ...
著者Brandstetter, H, Roedern, E.G.V, Grams, F, Engh, R.A.
登録日1998-04-03
公開日1999-04-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data.
Protein Sci., 7, 1998
1A86
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MMP8 WITH MALONIC AND ASPARTIC ACID BASED INHIBITOR
分子名称: CALCIUM ION, MMP-8, N-benzyl-N~2~-[(2R)-2-(hydroxycarbamoyl)-4-methylpentanoyl]-L-alpha-asparagine, ...
著者Brandstetter, H, Roedern, E.G.V, Grams, F, Engh, R.A.
登録日1998-04-03
公開日1999-05-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data.
Protein Sci., 7, 1998
1A87
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COLICIN N
分子名称: COLICIN N
著者Vetter, I.R, Parker, M.W, Tucker, A.D, Lakey, J.H, Pattus, F, Tsernoglou, D.
登録日1998-04-03
公開日1999-04-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of a colicin N fragment suggests a model for toxicity.
Structure, 6, 1998
1A88
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CHLOROPEROXIDASE L
分子名称: CHLOROPEROXIDASE L
著者Hofmann, B, Toelzer, S, Pelletier, I, Altenbuchner, J, Van Pee, K.-H, Hecht, H.-J.
登録日1998-04-03
公開日1998-10-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural investigation of the cofactor-free chloroperoxidases.
J.Mol.Biol., 279, 1998
1A8A
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RAT ANNEXIN V COMPLEXED WITH GLYCEROPHOSPHOSERINE
分子名称: ANNEXIN V, CALCIUM ION, L-ALPHA-GLYCEROPHOSPHORYLSERINE
著者Swairjo, M.A, Concha, N.O, Kaetzel, M.A, Dedman, J.R, Seaton, B.A.
登録日1998-03-23
公開日1998-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ca(2+)-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V.
Nat.Struct.Biol., 2, 1995
1A8B
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RAT ANNEXIN V COMPLEXED WITH GLYCEROPHOSPHOETHANOLAMINE
分子名称: ANNEXIN V, CALCIUM ION, L-ALPHA-GLYCEROPHOSPHORYLETHANOLAMINE
著者Swairjo, M.A, Concha, N.O, Kaetzel, M.A, Dedman, J.R, Seaton, B.A.
登録日1998-03-23
公開日1998-06-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ca(2+)-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V.
Nat.Struct.Biol., 2, 1995
1A8C
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PRIMARY SEQUENCE AND SOLUTION CONFORMATION OF FERROCYTOCHROME C-552 FROM NITROSOMONAS EUROPAEA, NMR, MEAN STRUCTURE REFINED WITHOUT HYDROGEN BOND CONSTRAINTS
分子名称: FERROCYTOCHROME C-552, HEME C
著者Timkovich, R, Bergmann, D, Arciero, D.M, Hooper, A.B.
登録日1998-03-23
公開日1998-10-21
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Primary sequence and solution conformation of ferrocytochrome c-552 from Nitrosomonas europaea.
Biophys.J., 75, 1998
1A8D
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TETANUS TOXIN C FRAGMENT
分子名称: GOLD ION, TETANUS NEUROTOXIN
著者Knapp, M, Rupp, B.
登録日1998-03-23
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The 1.61 Angstrom Structure of the Tetanus Toxin Ganglioside Binding Region: Solved by MAD and Mir Phase Combination
Am.Cryst.Assoc.,Abstr.Papers (Annual Meeting), 25, 1998
1A8E
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HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
分子名称: CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN
著者Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N.
登録日1998-03-24
公開日1998-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
1A8F
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HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
分子名称: CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN
著者Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N.
登録日1998-03-25
公開日1998-06-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
1A8G
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HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910
分子名称: HIV-1 PROTEASE, benzyl [(1R)-1-({(1S,2S,3S)-1-benzyl-2-hydroxy-4-({(1S)-1-[(2-hydroxy-4-methoxybenzyl)carbamoyl]-2-methylpropyl}amino)-3-[(4-methoxybenzyl)amino]-4-oxobutyl}carbamoyl)-2,2-dimethylpropyl]carbamate
著者Kallen, J, Billich, A, Scholz, D, Auer, M, Kungl, A.
登録日1998-03-24
公開日1998-07-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations.
J.Mol.Biol., 286, 1999
1A8H
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METHIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS
分子名称: METHIONYL-TRNA SYNTHETASE, ZINC ION
著者Sugiura, I, Nureki, O, Ugaji, Y, Kuwabara, S, Lober, B, Giege, R, Moras, D, Yokoyama, S, Konno, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日1998-03-26
公開日1999-05-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules.
Structure, 8, 2000
1A8I
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SPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE
分子名称: BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN, GLYCOGEN PHOSPHORYLASE B
著者Gregoriou, M, Noble, M.E.M, Watson, K.A, Garman, E.F, Krulle, T.M, De La Fuente, C, Fleet, G.W.J, Oikonomakos, N.G, Johnson, L.N.
登録日1998-03-25
公開日1998-07-01
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
Protein Sci., 7, 1998
1A8J
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IMMUNOGLOBULIN LAMBDA LIGHT CHAIN DIMER (MCG) COMPLEX WITH ASPARTAME
分子名称: IMMUNOGLOBULIN LAMBDA LIGHT CHAIN DIMER (MCG), N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER
著者Edmundson, A.B, Manion, C.V.
登録日1998-03-26
公開日1998-06-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Treatment of osteoarthritis with aspartame.
Clin.Pharmacol.Ther., 63, 1998
1A8K
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CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES
分子名称: HIV PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
著者Weber, I.T, Wu, J, Adomat, J, Harrison, R.W, Kimmel, A.R, Wondrak, E.M, Louis, J.M.
登録日1998-03-27
公開日1999-01-13
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic analysis of human immunodeficiency virus 1 protease with an analog of the conserved CA-p2 substrate -- interactions with frequently occurring glutamic acid residue at P2' position of substrates.
Eur.J.Biochem., 249, 1997
1A8L
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PROTEIN DISULFIDE OXIDOREDUCTASE FROM ARCHAEON PYROCOCCUS FURIOSUS
分子名称: PROTEIN DISULFIDE OXIDOREDUCTASE, ZINC ION
著者Ren, B, Tibbelin, G, Pascale, D, Rossi, M, Bartolucci, S, Ladenstein, R.
登録日1998-03-26
公開日1999-03-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units.
Nat.Struct.Biol., 5, 1998
1A8M
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TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT
分子名称: TUMOR NECROSIS FACTOR ALPHA
著者Reed, C, Fu, Z.-Q, Wu, J, Xue, Y.-N, Harrison, R.W, Chen, M.-J, Weber, I.T.
登録日1998-03-27
公開日1998-06-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2.
Protein Eng., 10, 1997
1A8N
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SOLUTION STRUCTURE OF A NA+ CATION STABILIZED DNA QUADRUPLEX CONTAINING G.G.G.G AND G.C.G.C TETRADS FORMED BY G-G-G-C REPEATS OBSERVED IN AAV AND HUMAN CHROMOSOME 19, NMR, 8 STRUCTURES
分子名称: DNA QUADRUPLEX CONTAINING G.G.G.G AND G.C.G.C TETRADS
著者Kettani, A, Bouaziz, S, Gorin, A, Zhao, H, Jones, R, Patel, D.J.
登録日1998-03-27
公開日1998-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a Na cation stabilized DNA quadruplex containing G.G.G.G and G.C.G.C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA.
J.Mol.Biol., 282, 1998
1A8O
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HIV CAPSID C-TERMINAL DOMAIN
分子名称: HIV CAPSID
著者Gamble, T.R, Yoo, S, Vajdos, F.F, Von Schwedler, U.K, Worthylake, D.K, Wang, H, Mccutcheon, J.P, Sundquist, W.I, Hill, C.P.
登録日1998-03-27
公開日1998-10-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
1A8P
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FERREDOXIN REDUCTASE FROM AZOTOBACTER VINELANDII
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH:FERREDOXIN OXIDOREDUCTASE
著者Prasad, G.S, Kresge, N, Muhlberg, A.B, Shaw, A, Jung, Y.S, Burgess, B.K, Stout, C.D.
登録日1998-03-28
公開日1998-06-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of NADPH:ferredoxin reductase from Azotobacter vinelandii.
Protein Sci., 7, 1998
1A8Q
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BROMOPEROXIDASE A1
分子名称: BROMOPEROXIDASE A1
著者Hofmann, B, Toelzer, S, Pelletier, I, Altenbuchner, J, Van Pee, K.-H, Hecht, H.-J.
登録日1998-03-27
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural investigation of the cofactor-free chloroperoxidases.
J.Mol.Biol., 279, 1998
1A8R
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GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP
分子名称: GTP CYCLOHYDROLASE I, GUANOSINE-5'-TRIPHOSPHATE
著者Auerbach, G, Nar, H, Bracher, A, Bacher, A, Huber, R.
登録日1998-03-27
公開日1999-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.
J.Mol.Biol., 326, 2003
1A8S
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CHLOROPEROXIDASE F/PROPIONATE COMPLEX
分子名称: CHLOROPEROXIDASE F, PROPANOIC ACID, SULFATE ION
著者Hofmann, B, Toelzer, S, Pelletier, I, Altenbuchner, J, Van Pee, K.-H, Hecht, H.-J.
登録日1998-03-27
公開日1998-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural investigation of the cofactor-free chloroperoxidases.
J.Mol.Biol., 279, 1998
1A8T
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METALLO-BETA-LACTAMASE IN COMPLEX WITH L-159,061
分子名称: 2-BUTYL-6-HYDROXY-3-[2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-3H-QUINAZOLIN-4-ONE, METALLO-BETA-LACTAMASE, ZINC ION
著者Fitzgerald, P.M.D, Toney, J.H, Grover, N, Vanderwall, D.
登録日1998-03-23
公開日1998-10-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase.
Chem.Biol., 5, 1998

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