7EJU
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7MC6
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![BU of 7mc6 by Molmil](/molmil-images/mine/7mc6) | Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex containing Mg2+ ion | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Moeller, N.M, Shi, K, Banerjee, S, Yin, L, Aihara, H. | 登録日 | 2021-04-01 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc.Natl.Acad.Sci.USA, 119, 2022
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7MC5
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![BU of 7mc5 by Molmil](/molmil-images/mine/7mc5) | Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, L(+)-TARTARIC ACID, ... | 著者 | Moeller, N.M, Shi, K, Banerjee, S, Yin, L, Aihara, H. | 登録日 | 2021-04-01 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc.Natl.Acad.Sci.USA, 119, 2022
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7MC9
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![BU of 7mc9 by Molmil](/molmil-images/mine/7mc9) | X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA | 分子名称: | 3C-like proteinase, Ubiquitin, ZINC ION, ... | 著者 | Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | 登録日 | 2021-04-01 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin Acta Cryst. D, 77, 2021
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7EIZ
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![BU of 7eiz by Molmil](/molmil-images/mine/7eiz) | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading | 分子名称: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | 著者 | Yan, L, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2021-04-01 | 公開日 | 2021-09-22 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading Cell, 184, 2021
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7EGQ
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![BU of 7egq by Molmil](/molmil-images/mine/7egq) | Co-transcriptional capping machineries in SARS-CoV-2 RTC: Coupling of N7-methyltransferase and 3'-5' exoribonuclease with polymerase reveals mechanisms for capping and proofreading | 分子名称: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | 著者 | Yan, L.M, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2021-03-25 | 公開日 | 2021-07-21 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading. Cell, 184, 2021
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7EG8
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![BU of 7eg8 by Molmil](/molmil-images/mine/7eg8) | TFIID-based core PIC on PUMA promoter | 分子名称: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGC
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![BU of 7egc by Molmil](/molmil-images/mine/7egc) | p53-bound TFIID-based holo PIC on HDM2 promoter | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGB
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![BU of 7egb by Molmil](/molmil-images/mine/7egb) | TFIID-based holo PIC on SCP promoter | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG7
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![BU of 7eg7 by Molmil](/molmil-images/mine/7eg7) | TFIID-based core PIC on SCP promoter | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG9
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![BU of 7eg9 by Molmil](/molmil-images/mine/7eg9) | TFIID-based intermediate PIC on SCP promoter | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGA
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![BU of 7ega by Molmil](/molmil-images/mine/7ega) | TFIID-based intermediate PIC on PUMA promoter | 分子名称: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EEI
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7EDX
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![BU of 7edx by Molmil](/molmil-images/mine/7edx) | p53-bound TFIID-based core PIC on HDM2 promoter | 分子名称: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-17 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7NW0
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![BU of 7nw0 by Molmil](/molmil-images/mine/7nw0) | RNA polymerase II pre-initiation complex with open promoter DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVZ
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![BU of 7nvz by Molmil](/molmil-images/mine/7nvz) | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | 分子名称: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVS
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![BU of 7nvs by Molmil](/molmil-images/mine/7nvs) | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVY
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![BU of 7nvy by Molmil](/molmil-images/mine/7nvy) | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | 分子名称: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVT
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![BU of 7nvt by Molmil](/molmil-images/mine/7nvt) | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVU
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![BU of 7nvu by Molmil](/molmil-images/mine/7nvu) | RNA polymerase II core pre-initiation complex with open promoter DNA | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7M1V
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![BU of 7m1v by Molmil](/molmil-images/mine/7m1v) | Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation | 分子名称: | 1,2-ETHANEDIOL, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, CHLORIDE ION, ... | 著者 | Aleshin, A.E, Shiryaev, S.A, Liddington, R.C. | 登録日 | 2021-03-15 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | To be provided To Be Published
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7ED5
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![BU of 7ed5 by Molmil](/molmil-images/mine/7ed5) | A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B. | 登録日 | 2021-03-15 | 公開日 | 2022-02-16 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase. Nat Commun, 13, 2022
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7NVR
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![BU of 7nvr by Molmil](/molmil-images/mine/7nvr) | Human Mediator with RNA Polymerase II Pre-initiation complex | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Rengachari, S, Schilbach, S, Aibara, S, Cramer, P. | 登録日 | 2021-03-15 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NUG
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7NUH
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