7NVR

Human Mediator with RNA Polymerase II Pre-initiation complex

Summary for 7NVR

• Entry DOI: 10.2210/pdb7nvr/pdb
• EMDB information: 12610
• Descriptor: TFIIH basal transcription factor complex helicase XPD subunit, Cyclin-H, DNA-directed RNA polymerase subunit, ... (61 entities in total)
• Functional Keywords: mediator complex, rna polymerase ii, tfiih, pre-initiation complex, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 58
• Total formula weight: 1978502.12

Authors

Rengachari, S.,Schilbach, S.,Aibara, S.,Cramer, P. (deposition date: 2021-03-15, release date: 2021-05-05, Last modification date: 2021-06-16)

• Primary citation: Aibara, S.,Schilbach, S.,Cramer, P.; Structures of mammalian RNA polymerase II pre-initiation complexes.; Nature, 594:124-128, 2021; PubMed: 33902107; DOI: 10.1038/s41586-021-03554-8

Experimental method

ELECTRON MICROSCOPY (4.5 Å)