7NW0

RNA polymerase II pre-initiation complex with open promoter DNA

Summary for 7NW0

Entry DOI	10.2210/pdb7nw0/pdb
Related	7NVS 7NVT 7NVU 7NVV 7NVW 7NVX 7NVZ
EMDB information	12611 12619 12624 12630
Descriptor	TFIIH basal transcription factor complex helicase XPD subunit, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase II subunit RPB3, ... (37 entities in total)
Functional Keywords	initiation, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	32
Total formula weight	1296393.45
Authors	Aibara, S.,Schilbach, S.,Cramer, P. (deposition date: 2021-03-16, release date: 2021-05-05, Last modification date: 2021-06-16)
Primary citation	Aibara, S.,Schilbach, S.,Cramer, P. Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594:124-128, 2021 Cited by PubMed: 33902107 DOI: 10.1038/s41586-021-03554-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.6 Å)

Structure validation