6EXN
 
 | | Post-catalytic P complex spliceosome with 3' splice site docked | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... | | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. | | 登録日 | 2017-11-08 | | 公開日 | 2018-01-17 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
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6EM1
 | | State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6ELZ
 | | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-09-30 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6QDV
 | | Human post-catalytic P complex spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. | | 登録日 | 2019-01-03 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Science, 363, 2019
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6CB1
 | | Yeast nucleolar pre-60S ribosomal subunit (state 3) | | 分子名称: | 35S pre-ribosomal RNA miscRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | 著者 | Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. | | 登録日 | 2018-02-01 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Modular assembly of the nucleolar pre-60S ribosomal subunit.
Nature, 556, 2018
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8HK1
 | | The cryo-EM structure of human pre-17S U2 snRNP | | 分子名称: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2022-11-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
Nat Commun, 14, 2023
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8H6K
 | | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6J
 | | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6E
 | | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-17 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6L
 | | Cryo-EM structure of human exon-defined spliceosome in the early B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8I9P
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Mak16 | | 分子名称: | 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9T
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9X
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9Z
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8HF0
 | | DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state | | 分子名称: | Dicer-2, isoform A, LD06392p, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2022-11-09 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
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8HF1
 | | DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state | | 分子名称: | Dicer-2, isoform A, LD06392p, ... | | 著者 | Su, S, Wang, J, Ma, J. | | 登録日 | 2022-11-09 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
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8IA0
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9R
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State 5S RNP | | 分子名称: | 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9V
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9W
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Dbp10-3 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9Y
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2 | | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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7Z52
 | | Human NEXT dimer - focused reconstruction of the single MTR4 | | 分子名称: | Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ... | | 著者 | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | | 登録日 | 2022-03-07 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
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7Z4Z
 | | Human NEXT dimer - focused reconstruction of the dimerization module | | 分子名称: | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8 | | 著者 | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | | 登録日 | 2022-03-06 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
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7Z4Y
 | | Human NEXT dimer - overall reconstruction of the core complex | | 分子名称: | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8 | | 著者 | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | | 登録日 | 2022-03-06 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
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8PJB
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