6EXN

Post-catalytic P complex spliceosome with 3' splice site docked

Summary for 6EXN

Entry DOI	10.2210/pdb6exn/pdb
Related	5MQ0 5MQF 5WSG 5XJC
EMDB information	3979
Descriptor	U2 snRNA, Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 45, ... (40 entities in total)
Functional Keywords	spliceosome, p-complex, exon ligation, splicing
Biological source	Saccharomyces cerevisiae S288c More
Total number of polymer chains	46
Total formula weight	2244126.52
Authors	Wilkinson, M.E.,Fica, S.M.,Galej, W.P.,Norman, C.M.,Newman, A.J.,Nagai, K. (deposition date: 2017-11-08, release date: 2018-01-17, Last modification date: 2020-10-07)
Primary citation	Wilkinson, M.E.,Fica, S.M.,Galej, W.P.,Norman, C.M.,Newman, A.J.,Nagai, K. Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science, 358:1283-1288, 2017 Cited by PubMed: 29146871 DOI: 10.1126/science.aar3729 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation