8HK1

The cryo-EM structure of human pre-17S U2 snRNP

Summary for 8HK1

• Entry DOI: 10.2210/pdb8hk1/pdb
• EMDB information: 34841
• Descriptor: U2 snRNA, Splicing factor 3A subunit 3, HIV Tat-specific factor 1, ... (23 entities in total)
• Functional Keywords: ddx42, u2 snrnp, spliceosome, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 1045136.66

Authors

Zhang, X.,Zhan, X.,Shi, Y. (deposition date: 2022-11-24, release date: 2023-03-08, Last modification date: 2023-08-16)

• Primary citation: Yang, F.,Bian, T.,Zhan, X.,Chen, Z.,Xing, Z.,Larsen, N.A.,Zhang, X.,Shi, Y.; Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.; Nat Commun, 14:897-897, 2023; PubMed: 36797247; DOI: 10.1038/s41467-023-36489-x

Experimental method

ELECTRON MICROSCOPY (2.7 Å)