PDB: 1507 件ウェブページステータス検索Chemie searchBIRD

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5E6J	Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe 分子名称: ACETATE ION, NICKEL (II) ION, Polyubiquitin-B, ... 著者 Lima, C.D, Bekes, M. 登録日 2015-10-09 公開日 2016-05-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease. Mol. Cell, 62, 2016
6A43	R1EN(5-225)-ubiquitin fusion 分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C 著者 Maita, N. 登録日 2018-06-19 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
6A44	R1EN(5-227)-ubiquitin fusion 分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C 著者 Maita, N. 登録日 2018-06-19 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
6A42	R1EN(5-223)-ubiquitin fusion 分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C 著者 Maita, N. 登録日 2018-06-19 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
6AQR	SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin 分子名称: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Morrow, M.E, Morgan, M.T, Wolberger, C. 登録日 2017-08-21 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins. EMBO Rep., 19, 2018
6B7M	Crystal structure of Legionella effector sdeD (lpg2509) in complex with Ubiquitin 分子名称: Polyubiquitin-C, SdeD (lpg2509) 著者 Mao, Y, Akturk, A, Wasilko, J. 登録日 2017-10-04 公開日 2018-04-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector. Nature, 557, 2018
6B7O	Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin 分子名称: Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Mao, Y, Akturk, A, Wasilko, J. 登録日 2017-10-04 公開日 2018-04-18 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector. Nature, 557, 2018
6ASR	REV1 UBM2 domain complex with ubiquitin 分子名称: DNA repair protein REV1, NICKEL (II) ION, Ubiquitin 著者 Miller, D.J. 登録日 2017-08-25 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.356 Å) 主引用文献 Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction. J. Mol. Biol., 430, 2018
6BI8	X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, GLYCEROL, ... 著者 Clasman, J.C, Mesecar, A.D. 登録日 2017-11-01 公開日 2018-11-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.291 Å) 主引用文献 Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease. Antiviral Res., 174, 2020
6BVB	Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C 分子名称: Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ... 著者 Tarade, D, Ohh, M, Lee, J.E. 登録日 2017-12-12 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease. Nat Commun, 9, 2018
6C16	Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex. 分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1 著者 Manczyk, N, Sicheri, F. 登録日 2018-01-04 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26, 2018
6BVA	Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex. 分子名称: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1 著者 Manczyk, N, Sicheri, F. 登録日 2017-12-12 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26, 2018
6BYH	Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex. 分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1 著者 Manczyk, N, Sicheri, F. 登録日 2017-12-20 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26, 2018
6CFP	CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE 分子名称: 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, Ubiquitin-like protein SMT3,Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-15 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE To Be Published
5HPK	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1 分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin variant NL.1 著者 Wu, K.-P, Mukherjee, M, Mercredi, P.Y, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.431 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
5HPL	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4 分子名称: Rsp5, Ubiquitin variant R5.4 著者 Wu, K.-P, Kamadurai, H.B, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
5HPS	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1 分子名称: Ubiquitin variant P1.1, WWP1 HECT 著者 Wu, K.-P, Mercredi, P.Y, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
5IBK	Skp1-F-box in complex with a ubiquitin variant 分子名称: F-box/WD repeat-containing protein 7, Polyubiquitin-B, S-phase kinase-associated protein 1,S-phase kinase-associated protein 1 著者 Orlicky, S, Sicheri, F. 登録日 2016-02-22 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proc.Natl.Acad.Sci.USA, 113, 2016
5JG6	APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C 分子名称: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION 著者 Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A. 登録日 2016-04-19 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.0013 Å) 主引用文献 Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
5J26	Crystal structure of a 53BP1 Tudor domain in complex with a ubiquitin variant 分子名称: Tumor suppressor p53-binding protein 1, Ubiquitin Variant i53 著者 Wan, L, Canny, M, Juang, Y.C, Durocher, D, Sicheri, F. 登録日 2016-03-29 公開日 2016-12-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5047 Å) 主引用文献 A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing To Be Published
5JQS	Crystal structure of deubiquitinase MINDY-1 in complex with Ubiquitin 分子名称: 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, Protein FAM63A, ... 著者 Abdul Rehman, S.A, Kulathu, Y. 登録日 2016-05-05 公開日 2016-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol.Cell, 63, 2016
5JP3	Structure of Xanthomonas campestris effector protein XopD bound to ubiquitin 分子名称: Polyubiquitin-B, Xanthomonas outer protein D 著者 Pruneda, J.N, Komander, D. 登録日 2016-05-03 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases. Mol.Cell, 63, 2016
5JTJ	USP7CD-CTP in complex with Ubiquitin 分子名称: CALCIUM ION, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin carboxyl-terminal hydrolase 7 著者 Murray, J.M, Rouge, L. 登録日 2016-05-09 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.321 Å) 主引用文献 Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation. Structure, 24, 2016
5JTV	USP7CD-UBL45 in complex with Ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Murray, J.M, Rouge, L. 登録日 2016-05-09 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.312 Å) 主引用文献 Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation. Structure, 24, 2016
4JQW	Crystal Structure of a Complex of NOD1 CARD and Ubiquitin 分子名称: Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C 著者 Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S. 登録日 2013-03-20 公開日 2014-03-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of a complex of NOD1 CARD and ubiquitin Plos One, 9, 2014

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