Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
6R2S
DownloadVisualize
BU of 6r2s by Molmil
The structure of Plasmodium vivax Duffy binding protein (PvDBP) bound to human antibody DB9
分子名称: Antibody DB9 heavy chain, Antibody DB9 light chain, Duffy receptor
著者Barber, N.M, Higgins, M.K.
登録日2019-03-18
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody.
Nat Microbiol, 4, 2019
6OAO
DownloadVisualize
BU of 6oao by Molmil
Structure of DBP in complex with human neutralizing antibody 092096
分子名称: Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
著者Urusova, D, Tolia, N.H.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.497 Å)
主引用文献Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
6OAN
DownloadVisualize
BU of 6oan by Molmil
Structure of DBP in complex with human neutralizing antibody 053054
分子名称: Antibody 053054 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
著者Urusova, D, Tolia, N.H.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
6S8T
DownloadVisualize
BU of 6s8t by Molmil
Structure of the ICAM-1-binding PfEMP1 IT4var13 DBLbeta domain
分子名称: Erythrocyte membrane protein 1
著者Lennartz, F, Higgins, M.K.
登録日2019-07-10
公開日2019-09-25
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S8U
DownloadVisualize
BU of 6s8u by Molmil
Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1, ...
著者Lennartz, F, Higgins, M.K.
登録日2019-07-10
公開日2019-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.67 Å)
主引用文献Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes.
Proc.Natl.Acad.Sci.USA, 116, 2019
7JGG
DownloadVisualize
BU of 7jgg by Molmil
Cryo-EM structure of P. falciparum VAR2CSA NF45 DBL5 and DBL6 domains at 4.88 A
分子名称: Erythrocyte membrane protein 1
著者Ma, R, Tolia, N.H.
登録日2020-07-19
公開日2021-01-13
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (4.88 Å)
主引用文献Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Nat Microbiol, 6, 2021
7JGF
DownloadVisualize
BU of 7jgf by Molmil
Cryo-EM structure of P. falciparum VAR2CSA FCR3 domains DBL5 and DBL6 at 4.69 A
分子名称: Erythrocyte membrane protein 1
著者Ma, R, Tolia, N.H.
登録日2020-07-19
公開日2021-01-13
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (4.69 Å)
主引用文献Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Nat Microbiol, 6, 2021
7JGE
DownloadVisualize
BU of 7jge by Molmil
Cryo-EM structure of P. falciparum VAR2CSA FCR3 core at 4 A
分子名称: Erythrocyte membrane protein 1
著者Ma, R, Tolia, N.H.
登録日2020-07-19
公開日2021-01-13
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Nat Microbiol, 6, 2021
7JGH
DownloadVisualize
BU of 7jgh by Molmil
Cryo-EM structure of P. falciparum VAR2CSA NF54 core in complex with CSA at 3.36 A
分子名称: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, Erythrocyte membrane protein 1, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid
著者Ma, R, Tolia, N.H.
登録日2020-07-19
公開日2021-01-13
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Nat Microbiol, 6, 2021
7JGD
DownloadVisualize
BU of 7jgd by Molmil
Cryo-EM structure of P. falciparum VAR2CSA FCR3 core at 3.4 A
分子名称: Erythrocyte membrane protein 1
著者Ma, R, Tolia, N.H.
登録日2020-07-19
公開日2021-01-13
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Nat Microbiol, 6, 2021
7B52
DownloadVisualize
BU of 7b52 by Molmil
VAR2CSA full ectodomain
分子名称: Erythrocyte membrane protein 1
著者Wang, K.T, Gourdon, P.E, Dagil, R, Salanti, A.
登録日2020-12-03
公開日2021-04-21
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
7B54
DownloadVisualize
BU of 7b54 by Molmil
VAR2CSA full ectodomain in present of plCS, DBL1-DBL4
分子名称: VAR2CSA in presence of plCS, DBl1-DBL4,Erythrocyte membrane protein 1
著者Wang, K.T, Dagil, R, Gourdon, P.E, Salanti, A.
登録日2020-12-03
公開日2021-06-02
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
7NNH
DownloadVisualize
BU of 7nnh by Molmil
Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6
分子名称: Erythrocyte membrane protein 1
著者Wang, K.T, Dagil, R, Salanti, A, Gourdon, P.E.
登録日2021-02-24
公開日2021-06-02
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
7FAS
DownloadVisualize
BU of 7fas by Molmil
VAR2CSA 3D7 ectodomain core region
分子名称: Erythrocyte membrane protein 1, PfEMP1
著者Wang, L, Zhaoning, W.
登録日2021-07-07
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
7FAP
DownloadVisualize
BU of 7fap by Molmil
Structure of VAR2CSA-CSA 3D7
分子名称: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1
著者Wang, L, Wang, Z.
登録日2021-07-07
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
Cell Discov, 7, 2021
7Z12
DownloadVisualize
BU of 7z12 by Molmil
VAR2 complex with PAM1.4
分子名称: PAM1.4, Heavy Chain, light Chain, ...
著者Raghavan, S.S.R, Wang, K.T.
登録日2022-02-24
公開日2022-11-02
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
7Z1H
DownloadVisualize
BU of 7z1h by Molmil
VAR2CSA APO
分子名称: VAR2CSA APO
著者Raghavan, S.S.R, Wang, K.T.
登録日2022-02-24
公開日2022-11-02
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
7Y09
DownloadVisualize
BU of 7y09 by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Shen, H, Ji, C, Xiao, J.
登録日2022-06-03
公開日2023-03-29
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
7Y0J
DownloadVisualize
BU of 7y0j by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum TM284VAR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 2 variant TM284var1, ...
著者Ji, C, Xiao, J.
登録日2022-06-05
公開日2023-04-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
7Y0H
DownloadVisualize
BU of 7y0h by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the P. falciparum VAR2CSA FCR3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1, ...
著者Ji, C, Xiao, J.
登録日2022-06-05
公開日2023-04-12
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
8A44
DownloadVisualize
BU of 8a44 by Molmil
Plasmodium vivax Duffy binding protein region II bound the DARC ectodomain and monoclonal antibody DB1
分子名称: Atypical chemokine receptor 1, Duffy binding protein, Heavy chain of monoclonal antibody DB1, ...
著者Moskovitz, R, Higgins, M.K.
登録日2022-06-10
公開日2023-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax.
Nat Commun, 14, 2023
7YG2
DownloadVisualize
BU of 7yg2 by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DBLMSP2, ...
著者Shen, H, Ji, C, Xiao, J.
登録日2022-07-09
公開日2023-03-29
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
8GZN
DownloadVisualize
BU of 8gzn by Molmil
IgM-var2CSA complex
分子名称: Erythrocyte membrane protein 1, Immunoglobulin J chain, Immunoglobulin heavy constant mu
著者Akhouri, R.R, Goel, S, Skoglund, U.
登録日2022-09-27
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-electron microscopy of IgM-VAR2CSA complex reveals IgM inhibits binding of Plasmodium falciparum to Chondroitin Sulfate A.
Nat Commun, 14, 2023
8C3Y
DownloadVisualize
BU of 8c3y by Molmil
HB3VAR03 apo headstructure (PfEMP1 A)
分子名称: PfEMP1
著者Raghavan, S.S.R, Lavstsen, T, Wang, K.T.
登録日2022-12-29
公開日2023-08-02
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
8C44
DownloadVisualize
BU of 8c44 by Molmil
HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ...
著者Raghavan, S.S.R, Lavstsen, T, Wang, K.T.
登録日2022-12-31
公開日2023-08-16
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
<12

 

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon