7B52

VAR2CSA full ectodomain

Summary for 7B52

• Entry DOI: 10.2210/pdb7b52/pdb
• Related: 7B54 7NNH
• EMDB information: 12017
• Descriptor: Erythrocyte membrane protein 1 (1 entity in total)
• Functional Keywords: var2csa, cell adhesion, malaria, pfemp1
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 307549.81

Authors

Wang, K.T.,Gourdon, P.E.,Dagil, R.,Salanti, A. (deposition date: 2020-12-03, release date: 2021-04-21, Last modification date: 2022-05-25)

• Primary citation: Wang, K.,Dagil, R.,Lavstsen, T.,Misra, S.K.,Spliid, C.B.,Wang, Y.,Gustavsson, T.,Sandoval, D.R.,Vidal-Calvo, E.E.,Choudhary, S.,Agerbaek, M.O.,Lindorff-Larsen, K.,Nielsen, M.A.,Theander, T.G.,Sharp, J.S.,Clausen, T.M.,Gourdon, P.,Salanti, A.; Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.; Nat Commun, 12:2956-2956, 2021; PubMed: 34011972; DOI: 10.1038/s41467-021-23254-1

Experimental method

ELECTRON MICROSCOPY (3.8 Å)