7B54

VAR2CSA full ectodomain in present of plCS, DBL1-DBL4

Summary for 7B54

Entry DOI	10.2210/pdb7b54/pdb
Related	7B52 7NNH
EMDB information	12017 12018 12477
Descriptor	VAR2CSA in presence of plCS, DBl1-DBL4,Erythrocyte membrane protein 1 (1 entity in total)
Functional Keywords	var2csa, cell adhesion, malaria, pfemp1, dbl
Biological source	Plasmodium falciparum More
Total number of polymer chains	1
Total formula weight	219438.56
Authors	Wang, K.T.,Dagil, R.,Gourdon, P.E.,Salanti, A. (deposition date: 2020-12-03, release date: 2021-06-02, Last modification date: 2022-05-25)
Primary citation	Wang, K.,Dagil, R.,Lavstsen, T.,Misra, S.K.,Spliid, C.B.,Wang, Y.,Gustavsson, T.,Sandoval, D.R.,Vidal-Calvo, E.E.,Choudhary, S.,Agerbaek, M.O.,Lindorff-Larsen, K.,Nielsen, M.A.,Theander, T.G.,Sharp, J.S.,Clausen, T.M.,Gourdon, P.,Salanti, A. Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12:2956-2956, 2021 Cited by PubMed: 34011972 DOI: 10.1038/s41467-021-23254-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation