Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

1W8A
DownloadVisualize
BU of 1w8a by Molmil
Third LRR domain of Drosophila Slit
分子名称: SLIT PROTEIN
著者Howitt, J.A, Clout, N.J, Hohenester, E.
登録日2004-09-17
公開日2004-10-25
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Binding Site for Robo Receptors Revealed by Dissection of the Leucine-Rich Repeat Region of Slit.
Embo J., 23, 2004
1XKU
DownloadVisualize
BU of 1xku by Molmil
Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin
著者Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J.
登録日2004-09-29
公開日2004-11-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
1P9A
DownloadVisualize
BU of 1p9a by Molmil
Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain precursor, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Varughese, K.I, Celikel, R, Ruggeri, Z.M.
登録日2003-05-09
公開日2003-07-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
4BST
DownloadVisualize
BU of 4bst by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P6122 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSS
DownloadVisualize
BU of 4bss by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSU
DownloadVisualize
BU of 4bsu by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4CNC
DownloadVisualize
BU of 4cnc by Molmil
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y.
登録日2014-01-21
公開日2014-02-26
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Structure, 22, 2014
4CNM
DownloadVisualize
BU of 4cnm by Molmil
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
著者Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y.
登録日2014-01-23
公開日2014-02-26
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Structure, 22, 2014
4BSR
DownloadVisualize
BU of 4bsr by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
1U0N
DownloadVisualize
BU of 1u0n by Molmil
The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex
分子名称: Botrocetin, Platelet glycoprotein Ib, Von Willebrand factor
著者Fukuda, K, Liddington, R.C.
登録日2004-07-13
公開日2005-04-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
5MX0
DownloadVisualize
BU of 5mx0 by Molmil
Crystal structure of human fibromodulin
分子名称: CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ...
著者Paracuellos, P, Hohenester, E.
登録日2017-01-20
公開日2017-03-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Matrix Biol., 63, 2017
4LXR
DownloadVisualize
BU of 4lxr by Molmil
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T.
登録日2013-07-30
公開日2014-04-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Proc.Natl.Acad.Sci.USA, 111, 2014
8REW
DownloadVisualize
BU of 8rew by Molmil
CryoEM structure of human GARP-lTGFbeta1 in complex with a Fab fragment derived from an activating antibody.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta activator LRRC32, ...
著者Felix, J, Lambert, F, Marien, L, van der Woning, B, Savvides, S.N, Lucas, S.
登録日2023-12-12
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献TGF-beta1 activating antibodies as novel immunotherapeutics for graft-versus-host disease.
To Be Published
8C7H
DownloadVisualize
BU of 8c7h by Molmil
Cryo-EM Map of the latTGF-beta LHG-10 Fab complex
分子名称: 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ...
著者Ebenhoch, R, Nar, H.
登録日2023-01-16
公開日2023-03-01
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro.
Immunohorizons, 7, 2023
6XFQ
DownloadVisualize
BU of 6xfq by Molmil
Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
分子名称: Platelet glycoprotein Ib alpha chain, Snaclec agglucetin subunit alpha-1, Snaclec agglucetin subunit beta-2
著者Wang, J, Gao, Y.X, Ke, J.Y, Zhu, Z.L, Niu, L.W.
登録日2020-06-16
公開日2021-06-23
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
To be published
6GFF
DownloadVisualize
BU of 6gff by Molmil
Structure of GARP (LRRC32) in complex with latent TGF-beta1 and MHG-8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat-containing protein 32, MHG-8 Fab heavy chain, ...
著者Merceron, R, Lienart, S, Vanderaa, C, Colau, D, Stockis, J, Van Der Woning, B, De Haard, H, Saunders, M, Coulie, P.G, Savvides, S.N, Lucas, S.
登録日2018-04-30
公開日2018-11-07
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of latent TGF-beta 1 presentation and activation by GARP on human regulatory T cells.
Science, 362, 2018
7WRQ
DownloadVisualize
BU of 7wrq by Molmil
Structure of Human IGF1/IGFBP3/ALS Ternary Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor-binding protein 3, Insulin-like growth factor-binding protein complex acid labile subunit, ...
著者Kim, H, Fu, Y, Kim, H.M.
登録日2022-01-27
公開日2022-08-10
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex
Nat Commun, 13, 2022
4LXS
DownloadVisualize
BU of 4lxs by Molmil
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T.
登録日2013-07-30
公開日2014-04-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Proc.Natl.Acad.Sci.USA, 111, 2014
1SQ0
DownloadVisualize
BU of 1sq0 by Molmil
Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin], Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II]
著者Dumas, J.J, Kumar, R, McDonagh, T, Sullivan, F, Stahl, M.L, Somers, W.S, Mosyak, L.
登録日2004-03-17
公開日2004-04-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
8I2H
DownloadVisualize
BU of 8i2h by Molmil
Follicle stimulating hormone receptor
分子名称: Follicle-stimulating hormone receptor
著者Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E.
登録日2023-01-14
公開日2023-03-22
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
8I2G
DownloadVisualize
BU of 8i2g by Molmil
FSHR-Follicle stimulating hormone-compound 716340-Gs complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E.
登録日2023-01-14
公開日2023-03-29
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
4MQW
DownloadVisualize
BU of 4mqw by Molmil
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ...
著者Jiang, X, Liu, H, Chen, X, He, X.
登録日2013-09-16
公開日2014-04-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.
J.Biol.Chem., 289, 2014
3PMH
DownloadVisualize
BU of 3pmh by Molmil
Mechanism of Sulfotyrosine-Mediated Glycoprotein Ib Interaction with Two Distinct alpha-Thrombin Sites
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, Platelet glycoprotein Ib alpha chain, ...
著者Varughese, K.I, Celikel, R.
登録日2010-11-16
公開日2011-06-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Proc.Natl.Acad.Sci.USA, 108, 2011
3G3A
DownloadVisualize
BU of 3g3a by Molmil
Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen
分子名称: Lysozyme C, Variable lymphocyte receptor VLRB.2D
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2009-02-02
公開日2009-06-23
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
8VSD
DownloadVisualize
BU of 8vsd by Molmil
avb8/L-TGF-b1/GARP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jin, M, Cheng, Y, Nishimura, S.L.
登録日2024-01-23
公開日2024-09-11
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 187, 2024

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon