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1XKU
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Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin
著者Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J.
登録日2004-09-29
公開日2004-11-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
1P9A
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BU of 1p9a by Molmil
Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain precursor, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Varughese, K.I, Celikel, R, Ruggeri, Z.M.
登録日2003-05-09
公開日2003-07-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
1XCD
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Dimeric bovine tissue-extracted decorin, crystal form 1
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin
著者Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J.
登録日2004-09-01
公開日2004-11-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
4BSS
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BU of 4bss by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSU
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Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BST
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Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P6122 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSR
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Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4CNC
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BU of 4cnc by Molmil
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y.
登録日2014-01-21
公開日2014-02-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Structure, 22, 2014
4CNM
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BU of 4cnm by Molmil
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
著者Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y.
登録日2014-01-23
公開日2014-02-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Structure, 22, 2014
8C7H
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BU of 8c7h by Molmil
Cryo-EM Map of the latTGF-beta 28G11 Fab complex
分子名称: 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ...
著者Ebenhoch, R, Nar, H.
登録日2023-01-16
公開日2023-03-01
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro.
Immunohorizons, 7, 2023
4LXR
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BU of 4lxr by Molmil
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T.
登録日2013-07-30
公開日2014-04-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Proc.Natl.Acad.Sci.USA, 111, 2014
7WRQ
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BU of 7wrq by Molmil
Structure of Human IGF1/IGFBP3/ALS Ternary Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor-binding protein 3, Insulin-like growth factor-binding protein complex acid labile subunit, ...
著者Kim, H, Fu, Y, Kim, H.M.
登録日2022-01-27
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex
Nat Commun, 13, 2022
6GFF
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BU of 6gff by Molmil
Structure of GARP (LRRC32) in complex with latent TGF-beta1 and MHG-8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat-containing protein 32, MHG-8 Fab heavy chain, ...
著者Merceron, R, Lienart, S, Vanderaa, C, Colau, D, Stockis, J, Van Der Woning, B, De Haard, H, Saunders, M, Coulie, P.G, Savvides, S.N, Lucas, S.
登録日2018-04-30
公開日2018-11-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of latent TGF-beta 1 presentation and activation by GARP on human regulatory T cells.
Science, 362, 2018
6XFQ
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BU of 6xfq by Molmil
Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
分子名称: Platelet glycoprotein Ib alpha chain, Snaclec agglucetin subunit alpha-1, Snaclec agglucetin subunit beta-2
著者Wang, J, Gao, Y.X, Ke, J.Y, Zhu, Z.L, Niu, L.W.
登録日2020-06-16
公開日2021-06-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
To be published
1SQ0
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Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin], Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II]
著者Dumas, J.J, Kumar, R, McDonagh, T, Sullivan, F, Stahl, M.L, Somers, W.S, Mosyak, L.
登録日2004-03-17
公開日2004-04-13
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
5MX0
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BU of 5mx0 by Molmil
Crystal structure of human fibromodulin
分子名称: CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ...
著者Paracuellos, P, Hohenester, E.
登録日2017-01-20
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Matrix Biol., 63, 2017
1U0N
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BU of 1u0n by Molmil
The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex
分子名称: Botrocetin, Platelet glycoprotein Ib, Von Willebrand factor
著者Fukuda, K, Liddington, R.C.
登録日2004-07-13
公開日2005-04-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
4LXS
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BU of 4lxs by Molmil
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T.
登録日2013-07-30
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Proc.Natl.Acad.Sci.USA, 111, 2014
3PMH
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BU of 3pmh by Molmil
Mechanism of Sulfotyrosine-Mediated Glycoprotein Ib Interaction with Two Distinct alpha-Thrombin Sites
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, Platelet glycoprotein Ib alpha chain, ...
著者Varughese, K.I, Celikel, R.
登録日2010-11-16
公開日2011-06-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Proc.Natl.Acad.Sci.USA, 108, 2011
8I2H
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Follicle stimulating hormone receptor
分子名称: Follicle-stimulating hormone receptor
著者Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E.
登録日2023-01-14
公開日2023-03-22
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
8I2G
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FSHR-Follicle stimulating hormone-compound 716340-Gs complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E.
登録日2023-01-14
公開日2023-03-29
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
3G3A
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Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen
分子名称: Lysozyme C, Variable lymphocyte receptor VLRB.2D
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2009-02-02
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3B
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Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen
分子名称: Lysozyme C, variable lymphocyte receptor VLRB.2D
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2009-02-02
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
4MQW
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Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ...
著者Jiang, X, Liu, H, Chen, X, He, X.
登録日2013-09-16
公開日2014-04-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.
J.Biol.Chem., 289, 2014
1P8V
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CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIISOPROPYL PHOSPHONATE, ...
著者Dumas, J.J, Kumar, R, Seehra, J, Somers, W.S, Mosyak, L.
登録日2003-05-07
公開日2003-07-22
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation
Science, 301, 2003

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