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4LXR

Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity

Summary for 4LXR
Entry DOI10.2210/pdb4lxr/pdb
Related3e07 4LXS
DescriptorProtein toll, Protein spaetzle C-106, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywordstlr, leucine-rich repeat, immune system, cytokine receptor, embryonic development, innate immunity, receptor-ligand complex', immune system-cytokine complex, immune system/cytokine
Biological sourceDrosophila melanogaster (Fruit fly)
More
Total number of polymer chains3
Total formula weight119557.35
Authors
Stelter, M.,Parthier, C.,Breithaupt, C.,Stubbs, M.T. (deposition date: 2013-07-30, release date: 2014-04-09, Last modification date: 2020-07-29)
Primary citationParthier, C.,Stelter, M.,Ursel, C.,Fandrich, U.,Lilie, H.,Breithaupt, C.,Stubbs, M.T.
Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Proc.Natl.Acad.Sci.USA, 111:6281-6286, 2014
Cited by
PubMed: 24733933
DOI: 10.1073/pnas.1320678111
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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